Synthesis of radiolabeled congeners of the carbomers: 14C-labeled poly(acrylic acid)s

Robert G. Riley, John D. Smart, John Tsibouklis*, J. Alf Davis, Grant Kelly, Frank Hampson, Peter W. Dettmar, William R. Wilber

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A general method for the synthesis of 14C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the 14C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.

Original languageEnglish
Pages (from-to)102-107
Number of pages6
JournalJournal of Biomedical Materials Research
Volume58
Issue number1
DOIs
Publication statusPublished - 24 Feb 2001

Keywords

  • C-label
  • Acrylic acid
  • Carbopol
  • Mucoadhesion
  • Poly(acrylic acid)

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