Synthesis of radiolabeled congeners of the carbomers: 14C-labeled poly(acrylic acid)s

Robert G. Riley; John D. Smart; John Tsibouklis; J. Alf Davis; Grant Kelly; Frank Hampson; Peter W. Dettmar; William R. Wilber

doi:10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0

Synthesis of radiolabeled congeners of the carbomers: ¹⁴C-labeled poly(acrylic acid)s

Robert G. Riley, John D. Smart, John Tsibouklis^*, J. Alf Davis, Grant Kelly, Frank Hampson, Peter W. Dettmar, William R. Wilber

^*Corresponding author for this work

Institute of Life Sciences and Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

A general method for the synthesis of ¹⁴C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the ¹⁴C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.

Original language	English
Pages (from-to)	102-107
Number of pages	6
Journal	Journal of Biomedical Materials Research
Volume	58
Issue number	1
DOIs	https://doi.org/10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0
Publication status	Published - 24 Feb 2001

Keywords

C-label
Acrylic acid
Carbopol
Mucoadhesion
Poly(acrylic acid)

Access to Document

10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0

Cite this

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title = "Synthesis of radiolabeled congeners of the carbomers: 14C-labeled poly(acrylic acid)s",

abstract = "A general method for the synthesis of 14C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the 14C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.",

keywords = "C-label, Acrylic acid, Carbopol, Mucoadhesion, Poly(acrylic acid)",

author = "Riley, \{Robert G.\} and Smart, \{John D.\} and John Tsibouklis and Davis, \{J. Alf\} and Grant Kelly and Frank Hampson and Dettmar, \{Peter W.\} and Wilber, \{William R.\}",

year = "2001",

month = feb,

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doi = "10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0",

language = "English",

volume = "58",

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T1 - Synthesis of radiolabeled congeners of the carbomers

T2 - 14C-labeled poly(acrylic acid)s

AU - Riley, Robert G.

AU - Smart, John D.

AU - Tsibouklis, John

AU - Davis, J. Alf

AU - Kelly, Grant

AU - Hampson, Frank

AU - Dettmar, Peter W.

AU - Wilber, William R.

PY - 2001/2/24

Y1 - 2001/2/24

N2 - A general method for the synthesis of 14C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the 14C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.

AB - A general method for the synthesis of 14C-acrylic acid is described in detail. The material is used for the synthesis of a range of radiolabeled poly(acrylic acid)s in which the 14C-label forms an integral part of the polymer backbone. The chemical structure of the synthesized polymers is examined in the light of spectroscopic data, molecular weight determinations, and rheological studies.

KW - C-label

KW - Acrylic acid

KW - Carbopol

KW - Mucoadhesion

KW - Poly(acrylic acid)

UR - https://www.scopus.com/pages/publications/0035130321

U2 - 10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0

DO - 10.1002/1097-4636(2001)58:1<102::AID-JBM150>3.0.CO;2-0

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VL - 58

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EP - 107

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JF - Journal of Biomedical Materials Research

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