Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda

J. Tassie; L. Pepper; Carole Fogg; S. Biraro; B. Mayanja; I. Andia; A. Paugam; G. Priotto; D. Legros

Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda

J. Tassie, L. Pepper, Carole Fogg, S. Biraro, B. Mayanja, I. Andia, A. Paugam, G. Priotto, D. Legros

School of Health & Care Professions

Research output: Contribution to journal › Article › peer-review

Abstract

In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.

Original language	English
Pages (from-to)	411-412
Number of pages	2
Journal	Journal of Acquired Immune Deficiency Syndromes
Volume	33
Issue number	3
Publication status	Published - 2003

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Cite this

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title = "Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda",

abstract = "In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.",

author = "J. Tassie and L. Pepper and Carole Fogg and S. Biraro and B. Mayanja and I. Andia and A. Paugam and G. Priotto and D. Legros",

year = "2003",

language = "English",

volume = "33",

pages = "411--412",

journal = "Journal of Acquired Immune Deficiency Syndromes",

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publisher = "Lippincott, Williams and Wilkins",

number = "3",

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TY - JOUR

T1 - Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda

AU - Tassie, J.

AU - Pepper, L.

AU - Fogg, Carole

AU - Biraro, S.

AU - Mayanja, B.

AU - Andia, I.

AU - Paugam, A.

AU - Priotto, G.

AU - Legros, D.

PY - 2003

Y1 - 2003

N2 - In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.

AB - In sub-Saharan Africa, cryptococcosis is a frequent opportunistic infection and a major cause of death in patients with AIDS. 1,2 The disease is mainly recognized at the neuromeningitis stage and is diagnosed by microscopy and culture of cerebrospinal fluid (CSF). The identification of cryptococcal antigen (CRAG) by latex particle agglutination is highly sensitive, 3,4 and this technique is used routinely in Western countries. We evaluated the prevalence of CRAG in serum samples from adults with clinically advanced HIV infection and the proportion of CRAG-positive patients with neuromeningitis.

M3 - Article

SN - 1525-4135

VL - 33

SP - 411

EP - 412

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

IS - 3

ER -

Systematic screening of cryptococcal antigenemia in HIV-positive adults in Uganda

Abstract

UN SDGs

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