The effect of super-oxidized water on Escherichia coli

Vitaly Zinkevich, I. Beech, R. Tapper, I. Bogdarina

Research output: Contribution to journalArticlepeer-review


The mechanism of action of Sterilox, a non-toxic liquid biocide produced by electrolysis of a dilute saline solution, upon planktonic cells of Escherichia coli JM109 was investigated using protein and nucleic acid analysis. The results revealed total destruction of chromosomal and plasmid DNA, RNA and proteins of E. coli within 5 min of exposure. Our earlier investigation conducted using atomic force microscopy imaging revealed swelling and rupture of E. coli cells with release of cytoplasm. We propose that the biocidal properties of Sterilox are due to its effect upon constituents of the bacterial cell including proteins and nucleic acids.
Original languageEnglish
Pages (from-to)153-156
Number of pages4
JournalJournal of Hospital Infection
Issue number2
Publication statusPublished - Oct 2000


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