The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

Kwai-Ming J. Cheung, Thomas P. Matthews, Karen Ball, Martin Rowlands, Kathy Boxall, Swee Sharp, Alison Maloney, S. Mark Roe, Chrisostomos Prodromou, Laurence Pearl, Wynne Aherne, Edward MacDonald, Paul Workman

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    Biochemistry, Genetics and Molecular Biology

    Pharmacology, Toxicology and Pharmaceutical Science