The novel use of resorbable Vicryl mesh for in vivo tendon reconstruction to a metal prosthesis

C J Pendegrass, M J Oddy, S Sundar, S R Cannon, A E Goodship, G W Blunn

Research output: Contribution to journalArticlepeer-review

Abstract

We examined the mechanical properties of Vicryl (polyglactin 910) mesh in vitro and assessed its use in vivo as a novel biomaterial to attach tendon to a hydroxyapatite-coated metal implant, the interface of which was augmented with autogenous bone and marrow graft. This was compared with tendon re-attachment using a compressive clamp device in an identical animal model. Two- and four-ply sleeves of Vicryl mesh tested to failure under tension reached 5.13% and 28.35% of the normal ovine patellar tendon, respectively. Four-ply sleeves supported gait in an ovine model with 67.05% weight-bearing through the operated limb at 12 weeks, without evidence of mechanical failure. Mesh fibres were visible at six weeks but had been completely resorbed by 12 weeks, with no evidence of chronic inflammation. The tendon-implant neoenthesis was predominantly an indirect type, with tendon attached to the bone-hydroxyapatite surface by perforating collagen fibres.

Original languageEnglish
Pages (from-to)1245-51
Number of pages7
JournalJournal of Bone and Joint Surgery - British Volume
Volume88
Issue number9
DOIs
Publication statusPublished - Sep 2006

Keywords

  • Animals
  • Biocompatible Materials
  • Cadaver
  • Coated Materials, Biocompatible
  • Durapatite
  • Equipment Design
  • Female
  • Hindlimb
  • Metals
  • Models, Anatomic
  • Patella
  • Polyglactin 910
  • Prosthesis Design
  • Prosthesis Implantation
  • Sheep
  • Surgical Mesh
  • Tendons
  • Tibia
  • Weight-Bearing

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