The partial volume effect in PET/SPECT and Benford's Law

Kevin Wells; John Chiverton; Mike Partridge; Miriam Barry; Haval Kadhem; Bob Ott

doi:10.1109/NSSMIC.2005.1596671

The partial volume effect in PET/SPECT and Benford's Law

Kevin Wells, John Chiverton, Mike Partridge, Miriam Barry, Haval Kadhem, Bob Ott

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

In this work we consider a probabilistic methodology that models the intensity distributions found in pure and partial volume (PV) voxels. We introduce some methodological developments that enable explicit modeling of the PV voxels prior probability density function (PDF). This new formulation can be applied generically across different imaging modalities including PET and SPECT. In this paper, we establish for the first time, that the prior PDF of voxels that arise from the PV effect in volumetric data can be well described by a simple phenomenological law called Benford's Law, which significantly eases parameter estimation compared to other methods. Results from simulated data are presented, along with a preliminary PET phantom study utilizing registered CT data to determine the quality of the resulting probabilistic voxel classification scheme.

Original language	English
Title of host publication	IEEE 2005 Nuclear Science Symposium and Medical Imaging Conference Record
Place of Publication	Piscataway
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1-5
Volume	3
ISBN (Print)	0780392213
DOIs	https://doi.org/10.1109/NSSMIC.2005.1596671
Publication status	Published - 2005

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10.1109/NSSMIC.2005.1596671

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title = "The partial volume effect in PET/SPECT and Benford's Law",

abstract = "In this work we consider a probabilistic methodology that models the intensity distributions found in pure and partial volume (PV) voxels. We introduce some methodological developments that enable explicit modeling of the PV voxels prior probability density function (PDF). This new formulation can be applied generically across different imaging modalities including PET and SPECT. In this paper, we establish for the first time, that the prior PDF of voxels that arise from the PV effect in volumetric data can be well described by a simple phenomenological law called Benford's Law, which significantly eases parameter estimation compared to other methods. Results from simulated data are presented, along with a preliminary PET phantom study utilizing registered CT data to determine the quality of the resulting probabilistic voxel classification scheme.",

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T1 - The partial volume effect in PET/SPECT and Benford's Law

AU - Wells, Kevin

AU - Chiverton, John

AU - Partridge, Mike

AU - Barry, Miriam

AU - Kadhem, Haval

AU - Ott, Bob

PY - 2005

Y1 - 2005

N2 - In this work we consider a probabilistic methodology that models the intensity distributions found in pure and partial volume (PV) voxels. We introduce some methodological developments that enable explicit modeling of the PV voxels prior probability density function (PDF). This new formulation can be applied generically across different imaging modalities including PET and SPECT. In this paper, we establish for the first time, that the prior PDF of voxels that arise from the PV effect in volumetric data can be well described by a simple phenomenological law called Benford's Law, which significantly eases parameter estimation compared to other methods. Results from simulated data are presented, along with a preliminary PET phantom study utilizing registered CT data to determine the quality of the resulting probabilistic voxel classification scheme.

AB - In this work we consider a probabilistic methodology that models the intensity distributions found in pure and partial volume (PV) voxels. We introduce some methodological developments that enable explicit modeling of the PV voxels prior probability density function (PDF). This new formulation can be applied generically across different imaging modalities including PET and SPECT. In this paper, we establish for the first time, that the prior PDF of voxels that arise from the PV effect in volumetric data can be well described by a simple phenomenological law called Benford's Law, which significantly eases parameter estimation compared to other methods. Results from simulated data are presented, along with a preliminary PET phantom study utilizing registered CT data to determine the quality of the resulting probabilistic voxel classification scheme.

U2 - 10.1109/NSSMIC.2005.1596671

DO - 10.1109/NSSMIC.2005.1596671

M3 - Conference contribution

SN - 0780392213

VL - 3

SP - 1

EP - 5

BT - IEEE 2005 Nuclear Science Symposium and Medical Imaging Conference Record

PB - Institute of Electrical and Electronics Engineers Inc.

CY - Piscataway

ER -

The partial volume effect in PET/SPECT and Benford's Law

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