The relationship between cobalt/chromium ratios and the high prevalence of head-stem junction corrosion in metal-on-metal total hip arthroplasty

Harry S Hothi; Reshid Berber; Robert K Whittaker; Gordon W Blunn; John A Skinner; Alister J Hart

doi:10.1016/j.arth.2015.11.014

The relationship between cobalt/chromium ratios and the high prevalence of head-stem junction corrosion in metal-on-metal total hip arthroplasty

Harry S Hothi, Reshid Berber, Robert K Whittaker, Gordon W Blunn, John A Skinner, Alister J Hart

School of Pharmacy & Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background - The size of the clinical impact of corrosion of the taper junction of metal-on-metal total hip arthroplasties (MOM-THAs) is unclear. Examination of a large number of retrieved MOM resurfacings and total hip arthroplasties can help us understand the role of taper corrosion in metal ion release.

Methods - We graded the severity of corrosion at the taper junction of 395 MOM-THAs and compared the prerevision whole blood metal ion levels of these hips with 529 failed MOM hip resurfacings.

Results - Virtually all MOM-THA hips (n = 388) had evidence of corrosion of the head-stem taper junction and graded as severe in 31% (n = 124). The median cobalt/chromium (Co/Cr) ratio was 1.58 (0.01-13.82) and 1.08 (0-4.86) for MOM-THA and MOM hip resurfacing, respectively; this difference was significant (P < .001). THA hips with severely corroded tapers had the highest median Co/Cr ratio of 1.86 (0.01-10).

Conclusions - This study demonstrates the high prevalence of severe taper corrosion, which may be related to an elevated Co/Cr ratio before revision.

Original language	English
Pages (from-to)	1123-1127
Number of pages	5
Journal	The Journal of Arthroplasty
Volume	31
Issue number	5
Early online date	26 Nov 2015
DOIs	https://doi.org/10.1016/j.arth.2015.11.014
Publication status	Published - May 2016

Keywords

Adult
Aged
Aged, 80 and over
Arthroplasty, Replacement, Hip
Chromium
Cobalt
Corrosion
Female
Hip Joint
Hip Prosthesis
Humans
Joint Diseases
Male
Metal-on-Metal Joint Prostheses
Middle Aged
Prosthesis Design
Prosthesis Failure
Retrospective Studies
Young Adult

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10.1016/j.arth.2015.11.014

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title = "The relationship between cobalt/chromium ratios and the high prevalence of head-stem junction corrosion in metal-on-metal total hip arthroplasty",

abstract = "Background - The size of the clinical impact of corrosion of the taper junction of metal-on-metal total hip arthroplasties (MOM-THAs) is unclear. Examination of a large number of retrieved MOM resurfacings and total hip arthroplasties can help us understand the role of taper corrosion in metal ion release.Methods - We graded the severity of corrosion at the taper junction of 395 MOM-THAs and compared the prerevision whole blood metal ion levels of these hips with 529 failed MOM hip resurfacings.Results - Virtually all MOM-THA hips (n = 388) had evidence of corrosion of the head-stem taper junction and graded as severe in 31% (n = 124). The median cobalt/chromium (Co/Cr) ratio was 1.58 (0.01-13.82) and 1.08 (0-4.86) for MOM-THA and MOM hip resurfacing, respectively; this difference was significant (P < .001). THA hips with severely corroded tapers had the highest median Co/Cr ratio of 1.86 (0.01-10).Conclusions - This study demonstrates the high prevalence of severe taper corrosion, which may be related to an elevated Co/Cr ratio before revision.",

keywords = "Adult, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip, Chromium, Cobalt, Corrosion, Female, Hip Joint, Hip Prosthesis, Humans, Joint Diseases, Male, Metal-on-Metal Joint Prostheses, Middle Aged, Prosthesis Design, Prosthesis Failure, Retrospective Studies, Young Adult",

author = "Hothi, {Harry S} and Reshid Berber and Whittaker, {Robert K} and Blunn, {Gordon W} and Skinner, {John A} and Hart, {Alister J}",

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T1 - The relationship between cobalt/chromium ratios and the high prevalence of head-stem junction corrosion in metal-on-metal total hip arthroplasty

AU - Hothi, Harry S

AU - Berber, Reshid

AU - Whittaker, Robert K

AU - Blunn, Gordon W

AU - Skinner, John A

AU - Hart, Alister J

N1 - Post-print is unavailable

PY - 2016/5

Y1 - 2016/5

N2 - Background - The size of the clinical impact of corrosion of the taper junction of metal-on-metal total hip arthroplasties (MOM-THAs) is unclear. Examination of a large number of retrieved MOM resurfacings and total hip arthroplasties can help us understand the role of taper corrosion in metal ion release.Methods - We graded the severity of corrosion at the taper junction of 395 MOM-THAs and compared the prerevision whole blood metal ion levels of these hips with 529 failed MOM hip resurfacings.Results - Virtually all MOM-THA hips (n = 388) had evidence of corrosion of the head-stem taper junction and graded as severe in 31% (n = 124). The median cobalt/chromium (Co/Cr) ratio was 1.58 (0.01-13.82) and 1.08 (0-4.86) for MOM-THA and MOM hip resurfacing, respectively; this difference was significant (P < .001). THA hips with severely corroded tapers had the highest median Co/Cr ratio of 1.86 (0.01-10).Conclusions - This study demonstrates the high prevalence of severe taper corrosion, which may be related to an elevated Co/Cr ratio before revision.

AB - Background - The size of the clinical impact of corrosion of the taper junction of metal-on-metal total hip arthroplasties (MOM-THAs) is unclear. Examination of a large number of retrieved MOM resurfacings and total hip arthroplasties can help us understand the role of taper corrosion in metal ion release.Methods - We graded the severity of corrosion at the taper junction of 395 MOM-THAs and compared the prerevision whole blood metal ion levels of these hips with 529 failed MOM hip resurfacings.Results - Virtually all MOM-THA hips (n = 388) had evidence of corrosion of the head-stem taper junction and graded as severe in 31% (n = 124). The median cobalt/chromium (Co/Cr) ratio was 1.58 (0.01-13.82) and 1.08 (0-4.86) for MOM-THA and MOM hip resurfacing, respectively; this difference was significant (P < .001). THA hips with severely corroded tapers had the highest median Co/Cr ratio of 1.86 (0.01-10).Conclusions - This study demonstrates the high prevalence of severe taper corrosion, which may be related to an elevated Co/Cr ratio before revision.

KW - Adult

KW - Aged

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KW - Corrosion

KW - Female

KW - Hip Joint

KW - Hip Prosthesis

KW - Humans

KW - Joint Diseases

KW - Male

KW - Metal-on-Metal Joint Prostheses

KW - Middle Aged

KW - Prosthesis Design

KW - Prosthesis Failure

KW - Retrospective Studies

KW - Young Adult

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DO - 10.1016/j.arth.2015.11.014

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SN - 0883-5403

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EP - 1127

JO - The Journal of Arthroplasty

JF - The Journal of Arthroplasty

IS - 5

ER -

The relationship between cobalt/chromium ratios and the high prevalence of head-stem junction corrosion in metal-on-metal total hip arthroplasty

Abstract

Keywords

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