Thyroid FNAC: causes of false-positive results

Daniela C. Malheiros; Sule Canberk; David Poller; Fernando Schmitt

doi:10.1111/cyt.12575

Thyroid FNAC: causes of false-positive results

Daniela C. Malheiros, Sule Canberk, David Poller, Fernando Schmitt

Research output: Contribution to journal › Article › peer-review

315 Downloads (Pure)

Abstract

In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity, “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP), is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.

Original language	English
Pages (from-to)	407-417
Number of pages	11
Journal	Cytopathology
Volume	29
Issue number	5
Early online date	16 May 2018
DOIs	https://doi.org/10.1111/cyt.12575
Publication status	Published - 1 Oct 2018

Keywords

thyroid FNA
false-positive
NIFTP
follicular-pattern lesions
thyroid carcinoma

Access to Document

10.1111/cyt.12575

Malheiros_et_al_2018
This is the peer reviewed version of the following article: Malheiros DC, Canberk S, Poller DN, Schmitt F. Thyroid FNAC: Causes of false‐positive results. Cytopathology. 2018;29:407–417, which has been published in final form at https://doi.org/10.1111/cyt.12575. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Accepted author manuscript (Post-print), 234 KB

Cite this

@article{81db39772fd24e13b9645bd512971169,

title = "Thyroid FNAC: causes of false-positive results",

abstract = "In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity, “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP), is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.",

keywords = "thyroid FNA, false-positive, NIFTP, follicular-pattern lesions, thyroid carcinoma",

author = "Malheiros, {Daniela C.} and Sule Canberk and David Poller and Fernando Schmitt",

year = "2018",

month = oct,

day = "1",

doi = "10.1111/cyt.12575",

language = "English",

volume = "29",

pages = "407--417",

journal = "Cytopathology",

issn = "0956-5507",

publisher = "Wiley",

number = "5",

}

TY - JOUR

T1 - Thyroid FNAC: causes of false-positive results

AU - Malheiros, Daniela C.

AU - Canberk, Sule

AU - Poller, David

AU - Schmitt, Fernando

PY - 2018/10/1

Y1 - 2018/10/1

N2 - In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity, “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP), is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.

AB - In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity, “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP), is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.

KW - thyroid FNA

KW - false-positive

KW - NIFTP

KW - follicular-pattern lesions

KW - thyroid carcinoma

U2 - 10.1111/cyt.12575

DO - 10.1111/cyt.12575

M3 - Article

SN - 0956-5507

VL - 29

SP - 407

EP - 417

JO - Cytopathology

JF - Cytopathology

IS - 5

ER -

Thyroid FNAC: causes of false-positive results

Abstract

Keywords

Access to Document

Fingerprint

Cite this