Thyroid FNAC: causes of false-positive results

Daniela C. Malheiros, Sule Canberk, David Poller, Fernando Schmitt

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Abstract

In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity, “noninvasive follicular thyroid neoplasm with papillary-like nuclear features” (NIFTP), is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.
Original languageEnglish
Pages (from-to)407-417
Number of pages11
JournalCytopathology
Volume29
Issue number5
Early online date16 May 2018
DOIs
Publication statusPublished - 1 Oct 2018

Keywords

  • thyroid FNA
  • false-positive
  • NIFTP
  • follicular-pattern lesions
  • thyroid carcinoma

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