Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery - An in Vitro Study in Human Femora

E. H. Van Haaren; T. H. Smit; K. Phipps; P. I J M Wuisman; G. Blunn; G. M. Insley; I. C. Heyligers

Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery - An in Vitro Study in Human Femora

E. H. Van Haaren^*, T. H. Smit, K. Phipps, P. I J M Wuisman, G. Blunn, G. M. Insley, I. C. Heyligers

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Impacted morsellised allografts have successfully been used to address the problem of poor bone stock in revision surgery. However, concern exists about pathogen transmission, high cost and shortage of supply of donor bone. Bone graft extenders, such as tricalciumphosphate (TCP) and hydroxyapatite (HA), have been developed to minimize the use of donor bone. In a human cadaver model we evaluated the surgical and mechanical feasibility of a TCP/HA bone graft extender during impaction grafting revision surgery. TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability as compared to bone graft alone (subsidence ratio graft : TCP/HA = 2.34). If surgeons are properly trained, this type of graft extender can be viable for impaction grafting revision surgery.

Original language	English
Pages (from-to)	667-670
Number of pages	4
Journal	Key Engineering Materials
Volume	254-256
Publication status	Published - 2004

Keywords

Bone grafting
Calcium phosphates
Hip
Materials testing
Surgical revision

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https://www.ncbi.nlm.nih.gov/pubmed/15736755

Cite this

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title = "Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery - An in Vitro Study in Human Femora",

abstract = "Impacted morsellised allografts have successfully been used to address the problem of poor bone stock in revision surgery. However, concern exists about pathogen transmission, high cost and shortage of supply of donor bone. Bone graft extenders, such as tricalciumphosphate (TCP) and hydroxyapatite (HA), have been developed to minimize the use of donor bone. In a human cadaver model we evaluated the surgical and mechanical feasibility of a TCP/HA bone graft extender during impaction grafting revision surgery. TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability as compared to bone graft alone (subsidence ratio graft : TCP/HA = 2.34). If surgeons are properly trained, this type of graft extender can be viable for impaction grafting revision surgery.",

keywords = "Bone grafting, Calcium phosphates, Hip, Materials testing, Surgical revision",

author = "{Van Haaren}, {E. H.} and Smit, {T. H.} and K. Phipps and Wuisman, {P. I J M} and G. Blunn and Insley, {G. M.} and Heyligers, {I. C.}",

year = "2004",

language = "English",

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pages = "667--670",

journal = "Key Engineering Materials",

issn = "1013-9826",

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T1 - Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery - An in Vitro Study in Human Femora

AU - Van Haaren, E. H.

AU - Smit, T. H.

AU - Phipps, K.

AU - Wuisman, P. I J M

AU - Blunn, G.

AU - Insley, G. M.

AU - Heyligers, I. C.

PY - 2004

Y1 - 2004

N2 - Impacted morsellised allografts have successfully been used to address the problem of poor bone stock in revision surgery. However, concern exists about pathogen transmission, high cost and shortage of supply of donor bone. Bone graft extenders, such as tricalciumphosphate (TCP) and hydroxyapatite (HA), have been developed to minimize the use of donor bone. In a human cadaver model we evaluated the surgical and mechanical feasibility of a TCP/HA bone graft extender during impaction grafting revision surgery. TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability as compared to bone graft alone (subsidence ratio graft : TCP/HA = 2.34). If surgeons are properly trained, this type of graft extender can be viable for impaction grafting revision surgery.

AB - Impacted morsellised allografts have successfully been used to address the problem of poor bone stock in revision surgery. However, concern exists about pathogen transmission, high cost and shortage of supply of donor bone. Bone graft extenders, such as tricalciumphosphate (TCP) and hydroxyapatite (HA), have been developed to minimize the use of donor bone. In a human cadaver model we evaluated the surgical and mechanical feasibility of a TCP/HA bone graft extender during impaction grafting revision surgery. TCP/HA allograft mix increased the risk of producing a fissure in the femur during the impaction procedure, but provided a higher initial mechanical stability as compared to bone graft alone (subsidence ratio graft : TCP/HA = 2.34). If surgeons are properly trained, this type of graft extender can be viable for impaction grafting revision surgery.

KW - Bone grafting

KW - Calcium phosphates

KW - Hip

KW - Materials testing

KW - Surgical revision

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M3 - Article

AN - SCOPUS:0348146009

SN - 1013-9826

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ER -

Tricalcium-Phosphate/Hydroxyapatite Bone Graft Extender for Use in Impaction Grafting Revision Surgery - An in Vitro Study in Human Femora

Abstract

Keywords

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