Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

Christian David Jorgensen

doi:10.1085/jgp.202413744

Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Elhanafy et al. used Molecular Dynamics simulations and electrophysiology to show how identical mutations in the volgage sending domain of sodium channels can yield differential functional effects.

Original language	English
Article number	e202413744
Number of pages	3
Journal	The Journal of General Physiology
Volume	157
Issue number	2
DOIs	https://doi.org/10.1085/jgp.202413744
Publication status	Published - 23 Jan 2025

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title = "Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders",

abstract = "Elhanafy et al. used Molecular Dynamics simulations and electrophysiology to show how identical mutations in the volgage sending domain of sodium channels can yield differential functional effects.",

author = "Jorgensen, {Christian David}",

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language = "English",

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AU - Jorgensen, Christian David

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N2 - Elhanafy et al. used Molecular Dynamics simulations and electrophysiology to show how identical mutations in the volgage sending domain of sodium channels can yield differential functional effects.

AB - Elhanafy et al. used Molecular Dynamics simulations and electrophysiology to show how identical mutations in the volgage sending domain of sodium channels can yield differential functional effects.

U2 - 10.1085/jgp.202413744

DO - 10.1085/jgp.202413744

M3 - Comment/debate

SN - 0022-1295

VL - 157

JO - The Journal of General Physiology

JF - The Journal of General Physiology

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M1 - e202413744

ER -

Understanding the role of mutations in voltage-gated sodium ion channels for cardiovascular disorders

Abstract

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