Use of cluster analysis to characterize patterns of sensitization in childhood allergy

Carina Venter, Kate Maslin, Hongmei Zhang, Akhilesh Kaushal, William Terry, Veeresh K Patil, Tara Dean, Syed Hasan Arshad

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Abstract

Multiple tests are available to determine food and aero‐allergen sensitization (1,2), but it is unclear if distinct sensitization patterns can be determined by using a combination of three testing modalities; skin prick test (SPT), specific IgE test and component resolved diagnostic tests to characterize or identify certain clinical phenotypes. This is a novel paper utilizing sensitization clusters (SPT, specific IgE tests and component resolved diagnostics) in an unselected cohort of 10/11 year‐old children and its association with asthma, eczema, rhinitis and IgE‐mediated food allergy. A birth cohort recruited in 2001 (Isle of Wight), was followed up prospectively to 10 years of age (3) (n = 827).
Original languageEnglish
Pages (from-to)644-648
Number of pages5
JournalPediatric Allergy and Immunology
Volume29
Issue number6
Early online date26 May 2018
DOIs
Publication statusPublished - 1 Sep 2018

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