If we are finally to end violence against women and girls (VAWG), then this commitment needs to be embedded into all development programmes regardless of sectorial focus. Women and girls are vulnerable across the board and recognition of this reality is the first step. The VAWG Mainstreaming Framework we propose here addresses how to centralise a VAWG lens into development programming irrespective of programmatic priorities. This article will evidence the need for such a lens and then present the approach through a number of stages. Finally the model will be applied to two programme areas, micro finance and HIV/Aids, demonstrating its applicability across development issues.