TY - JOUR
T1 - Xenopus resources: transgenic, inbred and mutant animals, training opportunities, and web-based support
AU - Centre de Ressource Biologique Xenope Team
AU - Horb, Marko
AU - Wlizla, Marzin
AU - Abu Daya, Anita
AU - McNamara, Sean
AU - Gajdasik, Dominika Weronika
AU - Igawa, Takeshi
AU - Ogino, Hajime
AU - Noble, Anna
AU - Suzuki, Atsushi
AU - Robert, Jacques
AU - James-Zorn, Christina
AU - Guille, Matt
PY - 2019/4/25
Y1 - 2019/4/25
N2 - Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.
AB - Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.
KW - RCUK
KW - BBSRC
KW - BB/R014841/1
U2 - 10.3389/fphys.2019.00387
DO - 10.3389/fphys.2019.00387
M3 - Article
SN - 1664-042X
VL - 10
JO - Frontiers in Physiology
JF - Frontiers in Physiology
M1 - 387
ER -