Xenopus resources: transgenic, inbred and mutant animals, training opportunities, and web-based support

Centre de Ressource Biologique Xenope Team, Marko Horb, Marzin Wlizla, Anita Abu Daya, Sean McNamara, Dominika Weronika Gajdasik, Takeshi Igawa, Hajime Ogino, Anna Noble, Atsushi Suzuki, Jacques Robert, Christina James-Zorn, Matt Guille

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Abstract

Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.
Original languageEnglish
Article number387
JournalFrontiers in Physiology
Volume10
DOIs
Publication statusPublished - 25 Apr 2019

Keywords

  • RCUK
  • BBSRC
  • BB/R014841/1

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