Zebrafish behavioral models of ageing

Alistair J. Brock, Ari Sudwarts, Matthew O. Parker, Caroline H. Brennan*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

Abstract

With lifespans rapidly increasing worldwide there has been a marked increase in age-related diseases-particularly those affecting cognition-that place a major socioeconomic burden on society. Despite this, much of what occurs during the aging process at a molecular level is poorly understood, facilitating the need for a greater understanding of the processes involved. In recent years, zebrafish have proved a useful model for the identification of genetic and cellular mechanisms affecting a variety of disease processes. Here we review the potential of zebrafish as a model for the study of cognitive ageing.

Original languageEnglish
Title of host publicationThe Rights and Wrongs of Zebrafish
Subtitle of host publicationBehavioral Phenotyping of Zebrafish
EditorsAllan V. Kalueff
PublisherSpringer International Publishing
Pages241-258
Number of pages18
ISBN (Electronic)9783319337746
ISBN (Print)9783319337739
DOIs
Publication statusPublished - 7 Feb 2017

Keywords

  • Ageing
  • Cognition
  • Degeneration
  • Memory
  • Zebrafish

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