With lifespans rapidly increasing worldwide there has been a marked increase in age-related diseases-particularly those affecting cognition-that place a major socioeconomic burden on society. Despite this, much of what occurs during the aging process at a molecular level is poorly understood, facilitating the need for a greater understanding of the processes involved. In recent years, zebrafish have proved a useful model for the identification of genetic and cellular mechanisms affecting a variety of disease processes. Here we review the potential of zebrafish as a model for the study of cognitive ageing.
|Title of host publication||The Rights and Wrongs of Zebrafish|
|Subtitle of host publication||Behavioral Phenotyping of Zebrafish|
|Editors||Allan V. Kalueff|
|Publisher||Springer International Publishing|
|Number of pages||18|
|Publication status||Published - 7 Feb 2017|