Abstract
After the introduction of sub-specialization in colorectal surgery, rectal cancer has acquired a unique position in terms of its diagnostic workup and further management. Despite the availability of multidisciplinary adjuncts to improve the outcomes in rectal cancer, prevention of postoperative complications remains the mainstay of effective surgical intervention. Different surgical and non- surgical treatment options have been tested and recommended at different stages of rectal cancer. The site and size of the cancers are also critical determinants in choosing the correct surgical procedure. A precise diagnostic workup is necessary as some low lying early rectal cancers may be suitable for organ preservation. In contrast, more advanced tumours at different rectal levels may require more extensive surgical procedures. The arguments about the suitability of a particular procedure and other intricacies depends on the characteristics of the tumour and essentially revolve around the following options.1.Organ preservation
2.Restorative resections
3.Non-restorative resections
I specialize in colorectal surgery and I have included eight publications in this thesis that particularly focus on the issues involving the management of rectal cancer rather than any other colorectal pathologies. Although, the procedures discussed form an integral core of surgical interventions, more alternatives need to be explored in future. The focal point in this thesis is to optimise the outcomes of surgical interventions by preventing the associated complications. This thesis adds to the existing knowledge through high-quality evidence on critical aspects of rectal cancer management.
| Date of Award | 11 Dec 2023 |
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| Original language | English |
| Awarding Institution |
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| Supervisor | Graham Mills (Supervisor) & Michael Harper (Supervisor) |