Imaging and tracking long distance transport of proteins such as molecular motors with conventional fluorescence methodologies is nearly impossible mainly due to photobleaching. In this work we demonstrate that DNA-SWNTs are very convenient tagging particles for in vivo tracking of proteins due to their low toxicity and bright and stable fluorescence. Also, soft lithography is used to build a microfluidic trap for in vivo fluorescence imaging in C.elegans.
|Date of Award||21 Dec 2011|
- Polytechnic University of Catalonia
- University of Barcelona
- Autonomous University of Barcelona
|Supervisor||Nikta Fakhri (Supervisor) & Dieter Klopfenstein (Supervisor)|