Use of single-walled carbon nanotubes for near-infrared fluorescence within inner tissues in C. elegans

Abstract

Imaging and tracking long distance transport of proteins such as molecular motors with conventional fluorescence methodologies is nearly impossible mainly due to photobleaching. In this work we demonstrate that DNA-SWNTs are very convenient tagging particles for in vivo tracking of proteins due to their low toxicity and bright and stable fluorescence. Also, soft lithography is used to build a microfluidic trap for in vivo fluorescence imaging in C.elegans.

Date of Award	21 Dec 2011
Original language	English
Awarding Institution	Polytechnic University of Catalonia University of Barcelona Autonomous University of Barcelona
Supervisor	Nikta Fakhri (Supervisor) & Dieter Klopfenstein (Supervisor)