School of Pharmacy and Biomedical Sciences
Organisational unit: School
The School of Pharmacy and Biomedical Science is one of the University's strongest areas of research. In the most recent research assessment round Portsmouth was in the top three for funding in England in the subject Allied Health Professions & Studies. Our researchers are contributing to the Institute of Biological and Biomedical Sciences (IBBS) where the majority of the research was rated internationally excellent or world-leading (3* and 4*).
There are a number of areas where our staff has made important contributions and discoveries. The major strengths of our current research portfolio lie in:
- Molecular Medicine (including oncology, the neurosciences and inherited diseases such as cystic fibrosis and muscular dystrophy)
- Medicines Research (drug development, targeting, safety, uses of natural products within medicine etc)
We clearly recognise that research, alongside teaching and the facilitation of learning, is a core academic activity. Such a diverse range of topics makes the School of Pharmacy and Biomedical Sciences a stimulating place for both learning and research.
The School makes a major contribution to multidisciplinary research across the university, notably the Institute of Biological and Biomedical Sciences (IBBS) and the University of Portsmouth Environmental Network (UPEN).
BIOMATERIALS AND DRUG DELIVERY
- Controlled and targeted drug delivery
- Biomolecular recognition
- Bioadhesion control
CELL BIOLOGY AND PHARMACOLOGY
- Investigating mechanisms and biomarkers of lung inflammation in cystic fibrosis, novel strategies to improve inhaled drug delivery and novel inhibitors of neutrophil elastase.
- glial cells in the brain, including oligodendroglia and their precursors in Multiple Sclerosis.
- Primary brain tumours as well as astrocytic response to various neuropathological conditions.
- Roles of Tensins in cancer and in neuronal/glial cell biology.
- Electrophysiology and biochemistry of ion channels, and their roles in the cellular physiology of human health and disease.
EPIGENETICS AND DEVELOPMENTAL BIOLOGY
- Molecular and Genetic Medicine, e.g. neuromuscular disease and neuronal function in disease, with particular emphasis on the molecular pathology of Duchenne muscular dystrophy and the role of dystrophin and related proteins.
- Control of neuronal identity and axon guidance in the early brain, and the genetic programming of muscle differentiation.
- Using Xenopus and chicken as model organisms, aimed at establishing the role of genes that are important in developmental processes.
- Role of pharmacists in multidisciplinary healthcare teams.
- Investigation into ways of making healthcare delivery cost-effective, more efficient and safer, for the benefit of patients.
- Risk management and pharmacovigilance
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