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Dr Alan Thorne

Associate Dean (Research)

  1. 2018
  2. Published

    Characterization and engineering of a plastic-degrading aromatic polyesterase

    Austin, H. P., Allen, M. D., Donohoe, B. S., Rorrer, N. A., Silveira, R., Kearns, F., Pollard, B., Dominick, G., Duman, R., Omari, K. E. & 11 others, Mykhaylyk, V., Wagner, A., Michener, W. E., Amore, A., Skaf, M. S., Crowley, M. F., Dr Alan Thorne, Woodcock, H. L., Johnson, C. W., Professor John McGeehan & Beckham, G. T., 8 May 2018, In : Proceedings of the National Academy of Sciences. 115, 19, p. E4350-E4357 8 p.

    Research output: Contribution to journalArticle

  3. 2016
  4. Published

    PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2BGlu2

    Grundy, G. J., Polo, L. M., Zeng, Z., Rulten, S. L., Hoch, N. C., Paomephan, P., Xu, Y., Sweet, S. M., Thorne, A. W., Oliver, A. W. & 3 others, Matthews, S. J., Pearl, L. H. & Caldecott, K. W., Aug 2016, In : Nature Communications. 7, 12404.

    Research output: Contribution to journalArticle

  5. 2015
  6. Published

    Calliphora vicina (Diptera: Calliphoridae) pupae: a timeline of external morphological development and a new age and PMI estimation tool

    Dr Katherine Brown, Dr Alan Thorne & Harvey, M., Jul 2015, In : International Journal of Legal Medicine. 129, 4, p. 835-850

    Research output: Contribution to journalArticle

  7. 2012
  8. Published

    Preservation of Calliphora vicina (Diptera: Calliphoridae) pupae for use in post-mortem interval estimation

    Dr Katherine Brown, Dr Alan Thorne & Harvey, M., 30 Nov 2012, In : Forensic Science International. 223, 1-3, p. 176-183 8 p.

    Research output: Contribution to journalArticle

  9. 2010
  10. Published

    Linker histone subtypes are not generalized gene repressors

    Trollope, A., Sapojnikova, N., Dr Alan Thorne, Professor Colyn Crane-Robinson & Dr Fiona Myers, 2010, In : Biochimica et Biophysica Acta. 1799, 9, p. 642-652 11 p.

    Research output: Contribution to journalArticle

  11. 2009
  12. Published

    The chromatin of active genes is not in a permanently open conformation

    Sapojnikova, N., Dr Alan Thorne, Dr Fiona Myers, Staynov, D. & Professor Colyn Crane-Robinson, 2009, In : Journal of Molecular Biology. 386, 2, p. 290-299 10 p.

    Research output: Contribution to journalArticle

  13. 2008
  14. Published

    The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression

    Zhang, X., Varthi, M., Sykes, S., Phillips, C., Warzecha, C., Zhu, W., Wyce, A., Dr Alan Thorne, Berger, S. & McMahon, S., 2008, In : Molecular Cell. 29, 1, p. 102-111 10 p.

    Research output: Contribution to journalArticle

  15. Published

    USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A

    Zhang, X., Pfeiffer, H., Dr Alan Thorne & McMahon, S., 2008, In : Cell Cycle. 7, 11, p. 1522-1524 3 p.

    Research output: Contribution to journalArticle

  16. 2007
  17. Published

    Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis

    Mann, J., Oakley, F., Akiboye, F., Elsharkawy, A., Dr Alan Thorne & Mann, D. A., 2007, In : Cell Death and Differentiation. 14, 2, p. 275-285 11 p.

    Research output: Contribution to journalArticle

  18. 2006
  19. Published

    Developmental activation of the lysozyme gene in chicken macrophage cells is linked to core histone acetylation at its enhancer elements

    Dr Fiona Myers, Lefevre, P., Mantouvalou, E., Bruce, K., Lacroix, C., Bonifer, C., Dr Alan Thorne & Professor Colyn Crane-Robinson, 2006, In : Nucleic Acids Research. 34, 14, p. 4025-4035 11 p.

    Research output: Contribution to journalArticle

  20. 2005
  21. Published

    Zygotic nucleosome assembly protein–like 1 has a specific, non–cell autonomous role in hematopoiesis

    Dr Anita Abu Daya, Steer, W., Trollope, A., Friedeberg, C., Patient, R., Dr Alan Thorne & Professor Matt Guille, 15 Jul 2005, In : Blood. 106, 2, p. 514-520 7 p.

    Research output: Contribution to journalArticle

  22. Published

    Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes

    Schneider, R., Bannister, A. J., Dr Fiona Myers, Dr Alan Thorne, Professor Colyn Crane-Robinson & Kouzarides, T., 6 May 2005, In : The Journal of Biological Chemistry. 280, 18, p. 17732-17736

    Research output: Contribution to journalArticle

  23. Published

    Biochemical observation of the rapid mobility of nuclear HMGB1

    Sapojnikova, N., Maman, J., Dr Fiona Myers, Dr Alan Thorne, Vorobyev, V. & Professor Colyn Crane-Robinson, 2005, In : Biochimica et Biophysica Acta. 1729, 1, p. 57-63 7 p.

    Research output: Contribution to journalArticle

  24. Published

    The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

    Bruce, K., Dr Fiona Myers, Mantouvalou, E., Lefevre, P., Greaves, I., Bonifer, C., Tremethick, D., Dr Alan Thorne & Professor Colyn Crane-Robinson, 2005, In : Nucleic Acids Research. 33, 17, p. 5633-5639 7 p.

    Research output: Contribution to journalArticle

  25. 2004
  26. Published

    A short-range gradient of histone H3 acetylation and Tup1p redistribution at the promoter of the Saccharomyces cerevisiae SUC2 gene

    Boukaba, A., Georgieva, E., Dr Fiona Myers, Dr Alan Thorne, Lopez-Rodas, G., Professor Colyn Crane-Robinson & Franco, L., 2004, In : The Journal of Biological Chemistry. 279, 9, p. 7678-7684 7 p.

    Research output: Contribution to journalArticle

  27. Published

    Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

    Schneider, R., Bannister, A. J., Dr Fiona Myers, Dr Alan Thorne, Professor Colyn Crane-Robinson & Kouzarides, T., 2004, In : Nature Cell Biology. 6, 1, p. 73-77

    Research output: Contribution to journalArticle

  28. Published

    Native chromatin immunoprecipitation

    Dr Alan Thorne, Dr Fiona Myers & Hebbes, T., 2004, Epigenetics protocols. Tollefsbol, T. (ed.). 287 ed. Totowa: Humana Press, p. 21-44 24 p. (Methods in molecular biology; no. 287).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  29. 2003
  30. Published

    Xenopus nucleosome assembly protein becomes tissue-restricted during development and can alter the expression of specific genes

    Steer, W. M., Dr Anita Abu Daya, Brickwood, S. J., Mumford, K. L., Jordanaires, N., Dr Julian Mitchell, Robinson, C., Dr Alan Thorne & Professor Matt Guille, Sep 2003, In : Mechanisms of Development. 120, 9, p. 1045-1057 13 p.

    Research output: Contribution to journalArticle

  31. Published

    Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor

    Lutz, M., Burke, L., Le Fevre, P., Dr Fiona Myers, Dr Alan Thorne, Professor Colyn Crane-Robinson, Bonifer, C., Filippova, G., Lobanenkov, V. & Renkawitz, R., 1 Apr 2003, In : EMBO Journal. 22, 7, p. 1579-1587 9 p.

    Research output: Contribution to journalArticle

  32. Published

    Acetylation of histone H2B mirrors that of H4 and H3 at the chicken β-Globin locus but not at housekeeping genes

    Dr Fiona Myers, Chong, W., Evans, D. R., Dr Alan Thorne & Professor Colyn Crane-Robinson, 2003, In : The Journal of Biological Chemistry. 278, 38, p. 36315-36322 8 p.

    Research output: Contribution to journalArticle

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