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Professor Anastasia Callaghan

Professor of Biochemistry and Molecular Biophysics

1 - 26 out of 26Page size: 50
  1. 1999
  2. Published

    Global conformational changes control the reactivity of methane monooxygenase

    S. Gallagher, Professor Anastasia Callaghan, J. Zhao, H. Dalton & J. Trewhella, 1999, In: Biochemistry. 38, 21, p. 6752-6760 9 p.

    Research output: Contribution to journal › Article › peer-review

  3. 2002
  4. Published

    Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase

    Professor Anastasia Callaghan, T. Smith, S. Slade & H. Dalton, 2002, In: European Journal Of Biochemistry. 269, 7, p. 1835-1843 9 p.

    Research output: Contribution to journal › Article › peer-review

  5. 2003
  6. Published

    Quaternary structure and catalytic activity of the Escherichia coli Ribonuclease E Amino-Terminal catalytic domain

    Professor Anastasia Callaghan, J. Gunter Grossmann, Y. Redko, L. Ilag, M. Moncrieffe, M. Symmons, Carol V. Robinson, K. McDowall & B. Luisi, 2003, In: Biochemistry. 42, 47, p. 13848-13855 8 p.

    Research output: Contribution to journal › Article › peer-review

  7. 2004
  8. Published

    Studies of the RNA degradosome-organizing domain of the Escherichia coli Ribonuclease RNase E

    Professor Anastasia Callaghan, J. Aurikko, L. Ilag, J. Gunter Grossmann, V. Chandran, K. Kuhnel, L. Poljak, A. Carpousis, Carol V. Robinson, M. Symmons & 1 others, B. Luisi, 2004, In: Journal of Molecular Biology. 340, 5, p. 965-979 15 p.

    Research output: Contribution to journal › Article › peer-review

  9. 2005
  10. Published

    Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover

    Professor Anastasia Callaghan, M. Marcaida, J. Stead, K. McDowall, W. Scott & B. Luisi, 2005, In: Nature. 437, 7062, p. 1187-1191 5 p.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    “Zn-Link”:  a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E

    Professor Anastasia Callaghan, Y. Redko, L. Murphy, J. Grossmann, D. Yates, E. Garman, L. Ilag, Carol V. Robinson, M. Symmons, K. McDowall & 1 others, B. Luisi, 2005, In: Biochemistry. 44, 12, p. 4667-4675 9 p.

    Research output: Contribution to journal › Article › peer-review

  12. 2008
  13. Published

    Complementing structural information of modular proteins with small angle neutron scattering and contrast variation

    J. Grossmann, Professor Anastasia Callaghan, M. Marcaida, B. Luisi, F. Alcock & K. Tokatlidis, 2008, In: European Biophysics Journal. 37, 5, p. 603-611 9 p.

    Research output: Contribution to journal › Article › peer-review

  14. Published

    The crystal structure of the Escherichia coli RNase E apoprotein and a mechanism for RNA degradation

    D. Koslover, Professor Anastasia Callaghan, M. Marcaida, E. Garman, M. Martick, W. Scott & B. Luisi, 2008, In: Structure. 16, 8, p. 1238-1244 7 p.

    Research output: Contribution to journal › Article › peer-review

  15. 2009
  16. Published

    Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly

    S. Nurmohamed, B. Vaidialingam, Professor Anastasia Callaghan & B. Luisi, 2009, In: Journal of Molecular Biology. 389, 1, p. 17-33 17 p.

    Research output: Contribution to journal › Article › peer-review

  17. 2010
  18. Published

    The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome

    M. Gorna, Z. Pietras, Y. Tsai, Professor Anastasia Callaghan, H. Hernandez, Carol V. Robinson & B. Luisi, 2010, In: RNA. 16, 3, p. 553-562 10 p.

    Research output: Contribution to journal › Article › peer-review

  19. 2011
  20. Published

    Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli

    S. Nurmohamed, Dr Helen Vincent, C. Titman, V. Chandran, M. Pears, D. Du, J. Griffin, Professor Anastasia Callaghan & B. Luisi, Apr 2011, In: The Journal of Biological Chemistry. 286, p. 14315-14323 9 p.

    Research output: Contribution to journal › Article › peer-review

  21. 2012
  22. Published

    Recognition of the 70S ribosome and polysome by the RNA degradosome in Escherichia coli

    Y-C. Tsai, D. Du, L. Dominguez-Malfavon, D. Dimastrogiovanni, J. Cross, Professor Anastasia Callaghan, J. Garcia-Mena & B. Luisi, 2012, In: Nucleic Acids Research. 40, 20, p. 10417-10431 15 p.

    Research output: Contribution to journal › Article › peer-review

  23. Published

    The low-resolution solution structure of Vibrio cholerae Hfq in complex with Qrr1 sRNA

    Dr Helen Vincent, Mrs Charlotte Henderson, C. Stone, Peter Cary, Dr Darren Gowers, F. Sobott, James E. Taylor & Professor Anastasia Callaghan, 2012, In: Nucleic Acids Research. 40, 17, p. 8698-8710 13 p.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region

    Dr Helen Vincent, Mrs Charlotte Henderson, T. Ragan, A. Garza-Garcia, Peter Cary, Dr Darren Gowers, M. Malfois, P. Driscoll, F. Sobott & Professor Anastasia Callaghan, 29 Jun 2012, In: Journal of Molecular Biology. 420, 1-2, p. 56-69 14 p.

    Research output: Contribution to journal › Article › peer-review

  25. 2013
  26. Published

    Characterization of MicA interactions suggests a potential novel means of gene regulation by small non-coding RNAs

    Mrs Charlotte Henderson, Dr Helen Vincent, Carlanne Stone, Jack Phillips, Peter Cary, Dr Darren Gowers & Professor Anastasia Callaghan, 2013, In: Nucleic Acids Research. 41, 5, p. 3386-3397 12 p.

    Research output: Contribution to journal › Article › peer-review

  27. Published

    Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS

    Mrs Charlotte Henderson, Dr Helen Vincent, A. Casamento, Carlanne Stone, Jack Phillips, Peter Cary, F. Sobott, Dr Darren Gowers, James E. Taylor & Professor Anastasia Callaghan, Aug 2013, In: RNA. 19, 8, p. 1089-1104 16 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing

    Dr Helen Vincent, Jack Phillips, Mrs Charlotte Henderson, Adam J. Roberts, Carlanne Stone, C. Mardle, Miss Louise Butt, Dr Darren Gowers, Professor Andrew Pickford & Professor Anastasia Callaghan, 14 Nov 2013, In: PLoS One. 8, 11, p. e79142

    Research output: Contribution to journal › Article › peer-review

  29. 2015
  30. Published

    The first small-molecule inhibitors of members of the ribonuclease E family

    Louise Kime, Dr Helen Vincent, Deena M. A. Gendoo, Stefanie S. Jourdan, Colin W. G. Fishwick, Professor Anastasia Callaghan & Kenneth J. Mcdowall, 26 Jan 2015, In: Scientific Reports. 5, 7 p., 8028.

    Research output: Contribution to journal › Article › peer-review

  31. 2017
  32. Published

    Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism

    Carlanne Stone, Miss Louise Butt, Joshua Bufton, Daniel C. Lourenco, Dr Darren Gowers, Professor Andrew Pickford, Professor Paul Cox, Dr Helen Vincent & Professor Anastasia Callaghan, 5 May 2017, In: Nucleic Acids Research. 45, 8, p. 4655-4666

    Research output: Contribution to journal › Article › peer-review

  33. 2018
  34. Published

    High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions

    Jack Phillips, Miss Louise Butt, Mrs Charlotte Henderson, Mr Martin Adrian Devonshire, Jess Healy, Stuart J. Conway, Nicolas Locker, Professor Andrew Pickford, Dr Helen Vincent & Professor Anastasia Callaghan, 21 Aug 2018, In: Nucleic Acids Research. 46, 14, 10 p., e86.

    Research output: Contribution to journal › Article › peer-review

  35. 2019
  36. Early online

    Application of mRNA arrays for the production of mCherry reporter-protein arrays for quantitative gene expression analysis

    Masoud Norouzi, Professor Andrew Pickford, Miss Louise Butt, Dr Helen Vincent & Professor Anastasia Callaghan, 25 Jan 2019, (Early online) In: ACS Synthetic Biology.

    Research output: Contribution to journal › Article › peer-review

  37. Published

    A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

    Charlotte E. Mardle, Thomas Jack Shakespeare, Miss Louise Butt, Miss Layla Goddard, Dr Darren Gowers, Helen S. Atkins, Dr Helen Vincent & Professor Anastasia Callaghan, 28 May 2019, In: Scientific Reports. 9, 1, 11 p., 7952.

    Research output: Contribution to journal › Article › peer-review

  38. Published

    Generation of small molecule-binding RNA arrays and their application to fluorogen-binding RNA aptamers

    Mrs Charlotte Henderson, Mr Callum Rail, Miss Louise Butt, Dr Helen Vincent & Professor Anastasia Callaghan, 1 Sep 2019, In: Methods. 167, p. 39-53

    Research output: Contribution to journal › Article › peer-review

  39. 2020
  40. Early online

    Identification and analysis of novel small molecule inhibitors of RNase E: implications for antibacterial targeting and regulation of RNase E

    Charlotte E. Mardle, Miss Layla Goddard, Bailei Claude Spelman, Helen S. Atkins, Miss Louise Butt, Professor Paul Cox, Dr Darren Gowers, Dr Helen Vincent & Professor Anastasia Callaghan, 9 Jun 2020, (Early online) In: Biochemistry and Biophysics Reports. 23, 100773.

    Research output: Contribution to journal › Article › peer-review

  41. 2021
  42. Published

    Identification of novel inhibitors of Escherichia coli DNA ligase

    Arqam Mohamad Azhar Msbah Alomari, Robert Michael Nicholas Gowland, Callum Southwood, Jak Barrow, Zoe Bentley, Jashel Calvin-Nelson, Alice Kaminski, Matthew LeFevre, Professor Anastasia Callaghan, Dr Helen Vincent & 1 others, Dr Darren Gowers, 25 Apr 2021, In: Molecules. 26, 9, 14 p., 2508.

    Research output: Contribution to journal › Article › peer-review

  43. Published

    An investigation into the potential of targeting Escherichia coli rne mRNA with locked nucleic acid (LNA) gapmers as an antibacterial strategy

    Miss Layla Goddard, Charlotte E. Mardle, Hassan Gneid, Miss Ciara Gina Ball, Dr Darren Gowers, Helen S. Atkins, Miss Louise Butt, Jonathan K. Watts, Dr Helen Vincent & Professor Anastasia Callaghan, 4 Jun 2021, In: Molecules. 26, 11, p. 1-15 15 p., 3414.

    Research output: Contribution to journal › Article › peer-review

ID: 25516