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Professor Geoff Pilkington

Emeritus Professor

  1. 2020
  2. Published

    A human co‐culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics

    Leite, D. M., Zvar Baskovic, B., Mr Prospero Civita, Neto, C., Gumbleton, M. & Professor Geoff Pilkington, 1 Jan 2020, In : FASEB Journal. 34, 1, p. 1710-1727 18 p.

    Research output: Contribution to journalArticle

  3. 2019
  4. Published
  5. Published

    Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood–brain barrier

    Aasen, S. N., Espedal, H., Holte, C. F., Keunen, O., Karlsen, T. V., Tenstad, O., Maherally, Z., Miletic, H., Hoang, T., Eikeland, A. V. & 8 others, Baghirov, H., Olberg, D. E., Professor Geoff Pilkington, Sarkar, G., Jenkins, R. B., Sundstrøm, T., Bjerkvig, R. & Thorsen, F., 1 Nov 2019, In : Molecular Cancer Therapeutics. 18, 11, p. 2171-2181 11 p.

    Research output: Contribution to journalArticle

  6. Early online

    Corrigendum to “IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.” [Cancer Lett. 458C (2019) 29–38]

    Mihajluk, K., Simms, C., Reay, M., Madureira, P. A., Howarth, A., Murray, P., Nasser, S., Duckworth, C. A., Pritchard, D. M., Pilkington, G. J. & 1 others, Hill, R., 8 Oct 2019, In : Cancer Letters.

    Research output: Contribution to journalComment/debate

  7. Published

    DIVERSet JAG compounds inhibit topoisomerase II and are effective against adult and pediatric high-grade gliomas

    Howarth, A., Simms, C., Kerai, N., Allen, O., Mihajluk, K., Madureira, P. A., Sokratous, G., Cragg, S., Lee, S. Y., Morley, A. D. & 4 others, Keyoumars, A., Dr Paul Cox, Professor Geoff Pilkington & Hill, R., 1 Oct 2019, In : Translational Oncology. 12, 10, p. 1375-1385

    Research output: Contribution to journalArticle

  8. Published

    IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas

    Mihajluk, K., Simms, C., Reay, M., Madureira, P. A., Howarth, A., Murray, P., Nasser, S., Duckworth, C. A., Pritchard, D. M., Pilkington, G. J. & 1 others, Hill, R., 28 Aug 2019, In : Cancer Letters. 458, p. 29-38 10 p.

    Research output: Contribution to journalArticle

  9. Published

    Integrated approach reveals role of mitochondrial germ-line mutation F18L in respiratory chain, oxidative alterations, drug sensitivity, and patient prognosis in glioblastoma

    Keatley, K., Stromei-Cleroux, S., Wiltshire, T., Rajala, N. K. M., Burton, G. D., Holt, W. V., Littlewood, D. T. J., Briscoe, A. G., Jung, J., Ashkan, K. & 6 others, Heales, S. J., Professor Geoff Pilkington, Meunier, B., Professor John McGeehan, Hargreaves, I. & Dr Rhiannon Lloyd, 9 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, 3364.

    Research output: Contribution to journalArticle

  10. Early online
  11. Early online

    Modulating autophagy as a therapeutic strategy for the treatment of paediatric high grade glioma

    Howarth, A., Dr Patricia Madureira, Lockwood, G., Storer, L. C. D., Grundy, R., Rahman, R., Professor Geoff Pilkington & Hill, R., 13 May 2019, In : Brain Pathology. 19 p.

    Research output: Contribution to journalReview article

  12. 2017
  13. Early online

    Immunohistochemical and flow cytometric analysis of intracellular and membrane-bound Hsp70, as a putative biomarker of glioblastoma multiforme, using the cmHsp70.1 monoclonal antibody

    Stangl, S., Foulds, G. A., Fellinger, H., Professor Geoff Pilkington, Pockley, A. G. & Multhoff, G., 26 Nov 2017, Chaperones: Methods and Protocols. Calderwood, S. & Prince, T. (eds.). New York: Humana Press, Vol. 1709. p. 307-320 14 p. (Methods in Molecular Biology; vol. 1709).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  14. Published

    The role of hypoxia in glioblastoma invasion

    Monteiro, A. R., Hill, R., Professor Geoff Pilkington & Dr Patricia Madureira, 22 Nov 2017, In : Stem Cells. 6, 4, 24 p., 45.

    Research output: Contribution to journalLiterature review

  15. Published

    Synthesis of biguanides and an investigation of their therapeutic effects on brain tumours

    Rita Buttrus, Haki, K., Eynon, M. F., Smith, A. J. S., Blazejczak, N. A., Professor Geoff Pilkington, Dr Peter Nunn, Higgins, S. & Dr James Smith, Oct 2017, p. 114.

    Research output: Contribution to conferenceAbstract

  16. Early online

    INSIDIA: a FIJI macro delivering high-throughput and high-content spheroid invasion analysis

    Moriconi, C., Palmieri, V., Di Santo, R., Tornillo, G., Papi, M., Professor Geoff Pilkington, De Spirito, M. & Gumbleton, M., 6 Sep 2017, In : Biotechnology Journal. 1700140.

    Research output: Contribution to journalArticle

  17. Published

    Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity

    Dr Zaynah Maherally, Dr Helen Fillmore, Tan, S. L., Tan, S. F., Jassam, S. A., Quack, F. I., Hatherell, K. E. & Professor Geoff Pilkington, Sep 2017, In : FASEB Journal. 32, 1, p. 168-182

    Research output: Contribution to journalArticle

  18. Published

    CD15s/CD62E interaction mediates the adhesion of non-small cell lung cancer cells on brain endothelial cells: implications for cerebral metastasis

    Jassam, S., Dr Zaynah Maherally, Dr James Smith, Ashkan, K., Roncaroli, F., Dr Helen Fillmore & Professor Geoff Pilkington, 10 Jul 2017, In : International Journal of Molecular Sciences. 18, 7, 1474.

    Research output: Contribution to journalArticle

  19. Published

    European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Weller, M., Van Den Bent, M., Tonn, J. C., Stupp, R., Preusser, M., Cohen-Jonathan-Moyal, E., Henriksson, R., Rhun, E. L., Balana, C., Chinot, O. & 16 others, Bendszus, M., Reijneveld, J. C., Dhermain, F., French, P., Marosi, C., Watts, C., Oberg, I., Professor Geoff Pilkington, Baumert, B. G., Taphoorn, M. J. B., Hegi, M., Westphal, M., Reifenberger, G., Soffietti, R., Wick, W. & European Association for Neuro-Oncology (EANO) Task Force on Gliomas, 1 Jun 2017, In : The Lancet Oncology. 18, 6, p. e315-e329

    Research output: Contribution to journalArticle

  20. Published

    Peptide nanofibers: targeted therapies for glioblastoma multiforme?

    Moreira Leite, D., Zhu, R., Barbu, E., Hinterdorfer, P., Professor Geoff Pilkington & Dr Katerina Lalatsa, 2 Apr 2017.

    Research output: Contribution to conferenceAbstract

  21. 2016
  22. Published

    Comparative gene expression profiling of ADAMs, MMPs, TIMPs, EMMPRIN, EGF-R and VEGFA in low grade meningioma

    Rooprai, H. K., Martin, A. J., King, A., Appadu, U. D., Jones, H., Selway, R. P., Gullan, R. W. & Professor Geoff Pilkington, Dec 2016, In : International Journal of Oncology. 49, 6, p. 2309-2318

    Research output: Contribution to journalArticle

  23. Published

    Drug repurposing to circumvent chemotherapy resistance in brain tumours

    Hill, R., Murray, S. A., Dr Zaynah Maherally, Higgins, S. C. & Professor Geoff Pilkington, 29 Nov 2016, Resistance to Targeted Therapies Against Adult Brain Cancers. Tivnan, A. (ed.). Springer International Publishing, p. 107-144 38 p. (Resistance to Targeted Therapies Against Adult Brain Cancers).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  24. Published

    Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells

    Vouri, M., Croucher, D. R., Kennedy, S. P., Dr Qian An, Professor Geoff Pilkington & Dr Sassan Hafizi, 24 Oct 2016, In : Oncogenesis. 5, 10, e266.

    Research output: Contribution to journalArticle

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