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Professor Geoff Pilkington

Emeritus Professor

  1. 2020
  2. Published

    A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): development of a preliminary checklist for evaluating quality and human relevance

    Mike Bracher, Professor Geoff Pilkington, C. Oliver Hanemann & Karen Pilkington, 7 Aug 2020, In : Frontiers in Bioengineering and Biotechnology. 8, 17 p., 936.

    Research output: Contribution to journalArticle

  3. Published

    A human co‐culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics

    Diana M. Leite, Barbara Zvar Baskovic, Prospero Civita, Catia Neto, Mark Gumbleton & Professor Geoff Pilkington, 1 Jan 2020, In : FASEB Journal. 34, 1, p. 1710-1727 18 p.

    Research output: Contribution to journalArticle

  4. 2019
  5. Published

    Pre-clinical drug testing in 2D and 3D human in vitro models of glioblastoma incorporating non-neoplastic astrocytes: tunneling nano tubules and mitochondrial transfer modulates cell behavior and therapeutic respons

    Prospero Civita, Diana M. Leite & Professor Geoff Pilkington, 29 Nov 2019, In : International Journal of Molecular Sciences. 20, 23, 24 p., 6017.

    Research output: Contribution to journalArticle

  6. Published

    Improved drug delivery to brain metastases by peptide-mediated permeabilization of the blood–brain barrier

    Synnøve Nymark Aasen, Heidi Espedal, Christopher Florian Holte, Olivier Keunen, Tine Veronika Karlsen, Olav Tenstad, Dr Zaynah Maherally, Hrvoje Miletic, Tuyen Hoang, Anne Vaag Eikeland & 8 others, Habib Baghirov, Dag Erlend Olberg, Professor Geoff Pilkington, Gobinda Sarkar, Robert B. Jenkins, Terje Sundstrøm, Rolf Bjerkvig & Frits Thorsen, 1 Nov 2019, In : Molecular Cancer Therapeutics. 18, 11, p. 2171-2181 11 p.

    Research output: Contribution to journalArticle

  7. Early online

    Corrigendum to “IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.” [Cancer Lett. 458C (2019) 29–38]

    K. Mihajluk, C. Simms, M. Reay, Dr Patricia Madureira, A. Howarth, P. Murray, S. Nasser, C.A. Duckworth, D.M. Pritchard, Professor Geoff Pilkington & 1 others, R. Hill, 8 Oct 2019, In : Cancer Letters.

    Research output: Contribution to journalComment/debate

  8. Published

    DIVERSet JAG compounds inhibit topoisomerase II and are effective against adult and pediatric high-grade gliomas

    Alison Howarth, Claire Simms, Nitesh Kerai, Olivia Allen, Karina Mihajluk, Dr Patricia Madureira, Giannis Sokratous, Professor Simon Cragg, Sang Y. Lee, Andy D. Morley & 4 others, Ashkan Keyoumars, Professor Paul Cox, Professor Geoff Pilkington & Richard Hill, 1 Oct 2019, In : Translational Oncology. 12, 10, p. 1375-1385

    Research output: Contribution to journalArticle

  9. Published

    IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas

    K. Mihajluk, C. Simms, M. Reay, Dr Patricia Madureira, A. Howarth, P. Murray, S. Nasser, C. A. Duckworth, D. M. Pritchard, Professor Geoff Pilkington & 1 others, R. Hill, 28 Aug 2019, In : Cancer Letters. 458, p. 29-38 10 p.

    Research output: Contribution to journalArticle

  10. Published

    Integrated approach reveals role of mitochondrial germ-line mutation F18L in respiratory chain, oxidative alterations, drug sensitivity, and patient prognosis in glioblastoma

    Kathleen Keatley, Samuel Stromei-Cleroux , Tammy Wiltshire, Nina Katja Maria Rajala, Gary David Burton, William V. Holt, D. Timothy J. Littlewood, Andrew G. Briscoe, Josephine Jung, Keyoumars Ashkan & 6 others, Simon J. Heales, Professor Geoff Pilkington, Brigitte Meunier, Professor John McGeehan, Iain Hargreaves & Dr Rhiannon Lloyd, 9 Jul 2019, In : International Journal of Molecular Sciences. 20, 13, 3364.

    Research output: Contribution to journalArticle

  11. Early online
  12. Early online

    Modulating autophagy as a therapeutic strategy for the treatment of paediatric high grade glioma

    Alison Howarth, Dr Patricia Madureira, George Lockwood, Lisa C. D. Storer, Richard Grundy, Ruman Rahman, Professor Geoff Pilkington & Richard Hill, 13 May 2019, In : Brain Pathology. 19 p.

    Research output: Contribution to journalReview article

  13. 2017
  14. Early online

    Immunohistochemical and flow cytometric analysis of intracellular and membrane-bound Hsp70, as a putative biomarker of glioblastoma multiforme, using the cmHsp70.1 monoclonal antibody

    Stefan Stangl, Gemma A. Foulds, Helena Fellinger, Professor Geoff Pilkington, A. Graham Pockley & Gabriele Multhoff, 26 Nov 2017, Chaperones: Methods and Protocols. Calderwood, S. & Prince, T. (eds.). New York: Humana Press, Vol. 1709. p. 307-320 14 p. (Methods in Molecular Biology; vol. 1709).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  15. Published

    The role of hypoxia in glioblastoma invasion

    Ana Rita Monteiro, Richard Hill, Professor Geoff Pilkington & Dr Patricia Madureira, 22 Nov 2017, In : Stem Cells. 6, 4, 24 p., 45.

    Research output: Contribution to journalLiterature review

  16. Published

    Synthesis of biguanides and an investigation of their therapeutic effects on brain tumours

    Rita N. Buttrus, Kani Haki, Megan F. Eynon, Ashleigh J. S. Smith, Natalia A. Blazejczak, Professor Geoff Pilkington, Dr Peter Nunn, Samantha Higgins & Dr James Smith, Oct 2017, p. 114.

    Research output: Contribution to conferenceAbstract

  17. Early online

    INSIDIA: a FIJI macro delivering high-throughput and high-content spheroid invasion analysis

    Chiara Moriconi, Valentina Palmieri, Riccardo Di Santo, Giusy Tornillo, Massimiliano Papi, Professor Geoff Pilkington, Marco De Spirito & Mark Gumbleton, 6 Sep 2017, In : Biotechnology Journal. 1700140.

    Research output: Contribution to journalArticle

  18. Published

    Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity

    Dr Zaynah Maherally, Dr Helen Fillmore, Sim Ling Tan, Suk Fei Tan, Samah A. Jassam, Friederike I. Quack, Kathryn E. Hatherell & Professor Geoff Pilkington, Sep 2017, In : FASEB Journal. 32, 1, p. 168-182

    Research output: Contribution to journalArticle

  19. Published

    CD15s/CD62E interaction mediates the adhesion of non-small cell lung cancer cells on brain endothelial cells: implications for cerebral metastasis

    Samah Jassam, Dr Zaynah Maherally, Dr James Smith, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, 10 Jul 2017, In : International Journal of Molecular Sciences. 18, 7, 1474.

    Research output: Contribution to journalArticle

  20. Published

    European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Michael Weller, Martin Van Den Bent, Jörg C. Tonn, Roger Stupp, Matthias Preusser, Elizabeth Cohen-Jonathan-Moyal, Roger Henriksson, Emilie Le Rhun, Carmen Balana, Olivier Chinot & 16 others, Martin Bendszus, Jaap C. Reijneveld, Frederick Dhermain, Pim French, Christine Marosi, Colin Watts, Ingela Oberg, Professor Geoff Pilkington, Brigitta G. Baumert, Martin J. B. Taphoorn, Monika Hegi, Manfred Westphal, Guido Reifenberger, Riccardo Soffietti, Wolfgang Wick & European Association for Neuro-Oncology (EANO) Task Force on Gliomas European Association for Neuro-Oncology (EANO) Task Force on Gliomas, 1 Jun 2017, In : The Lancet Oncology. 18, 6, p. e315-e329

    Research output: Contribution to journalArticle

  21. Published

    Peptide nanofibers: targeted therapies for glioblastoma multiforme?

    Diana Moreira Leite, Rong Zhu, Eugen Barbu, Peter Hinterdorfer, Professor Geoff Pilkington & Dr Katerina Lalatsa, 2 Apr 2017.

    Research output: Contribution to conferenceAbstract

  22. 2016
  23. Published

    Comparative gene expression profiling of ADAMs, MMPs, TIMPs, EMMPRIN, EGF-R and VEGFA in low grade meningioma

    Harcharan K. Rooprai, Andrew J. Martin, Andrew King, Usha D. Appadu, Huw Jones, Richard P. Selway, Richard W. Gullan & Professor Geoff Pilkington, Dec 2016, In : International Journal of Oncology. 49, 6, p. 2309-2318

    Research output: Contribution to journalArticle

  24. Published

    Drug repurposing to circumvent chemotherapy resistance in brain tumours

    Richard Hill, Samantha A. Murray, Dr Zaynah Maherally, Samantha C. Higgins & Professor Geoff Pilkington, 29 Nov 2016, Resistance to Targeted Therapies Against Adult Brain Cancers. Tivnan, A. (ed.). Springer International Publishing, p. 107-144 38 p. (Resistance to Targeted Therapies Against Adult Brain Cancers).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

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