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Dr Helen Fillmore

Reader in Molecular Neuropathology and Neuro-oncology

  1. 2019
  2. Published

    Human Sialic acid O-acetyl esterase (SIAE) – mediated changes in sensitivity to etoposide in a medulloblastoma cell line

    Rebecca L. Mather, Katie Loveson & Dr Helen Fillmore, 13 Jun 2019, In : Scientific Reports. 9, 8609.

    Research output: Contribution to journalArticle

  3. Early online
  4. 2018
  5. Published

    Intersection of brain development and paediatric diffuse midline gliomas: potential role of microenvironment in tumour growth

    Katie Loveson & Dr Helen Fillmore, 16 Nov 2018, In : Brain Sciences. 8, 11, 200.

    Research output: Contribution to journalArticle

  6. Published

    Current insights into Matrix metalloproteinases and glioma progression: transcending the degradation boundary

    N. Pullen, Dr Andrew Pickford, M. M. Perry, D. M. Jaworski, K. Loveson, Mr Daniel Arthur, J. Holliday, T. Van Meter, R. Peckham, W. Younas & 5 others, S. Briggs, S. MacDonald, T. Butterfield, M. Constantinou & Dr Helen Fillmore, 17 Sep 2018, In : Metalloproteinases in Medicine. 5, p. 13-30

    Research output: Contribution to journalArticle

  7. Published

    Oxamate, but not selective targeting of LDH-A, inhibits medulloblastoma cell glycolysis, growth and motility

    Cara Valvona & Dr Helen Fillmore, Apr 2018, In : Brain Sciences. 8, 4, 56.

    Research output: Contribution to journalArticle

  8. 2017
  9. Published

    Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity

    Dr Zaynah Maherally, Dr Helen Fillmore, Sim Ling Tan, Suk Fei Tan, Samah A. Jassam, Friederike I. Quack, Kathryn E. Hatherell & Professor Geoff Pilkington, Sep 2017, In : FASEB Journal. 32, 1, p. 168-182

    Research output: Contribution to journalArticle

  10. Published

    CD15s/CD62E interaction mediates the adhesion of non-small cell lung cancer cells on brain endothelial cells: implications for cerebral metastasis

    Samah Jassam, Dr Zaynah Maherally, Dr James Smith, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, 10 Jul 2017, In : International Journal of Molecular Sciences. 18, 7, 1474.

    Research output: Contribution to journalArticle

  11. 2016
  12. Published

    TNF-a enhancement of CD62E mediates adhesion of non-small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis

    Samah Ali Jassam, Dr Zaynah Maherally, Dr James Smith, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, May 2016, In : Neuro-Oncology. 18, 5, p. 679-690 12 p.

    Research output: Contribution to journalArticle

  13. Published

    AFM observation of heightened cell periphery of high-grade glioblastoma cell lines

    Dr James Smith, Dr Zaynah Maherally, Samantha C. Higgins, Dr Qian An, Dr Helen Fillmore & Professor Geoff Pilkington, Mar 2016, In : BioNanoScience. 6, 1, p. 47-53

    Research output: Contribution to journalArticle

  14. Published
  15. Published

    NSCLC Cell Adhesion to and Transmigration through Brain Endothelium in Brain Metastasis

    Samah Ali Jassam, Dr Zaynah Maherally, Dr Helen Fillmore & Professor Geoff Pilkington, Jan 2016, WFNOS Magazine, 1, 1, p. 2-6 5 p.

    Research output: Contribution to specialist publicationArticle

  16. Published

    The regulation and function of Lactate Dehydrogenase A: therapeutic potential in brain tumor

    Cara Valvona, Dr Helen Fillmore, Dr Peter Nunn & Professor Geoff Pilkington, Jan 2016, In : Brain Pathology. 26, 1, p. 3-17

    Research output: Contribution to journalArticle

  17. 2015
  18. Published

    Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro

    Samantha C. Higgins, Dr Helen Fillmore, Keyoumars Ashkan, Professor Arthur Butt & Professor Geoff Pilkington, Jan 2015, In : Anticancer Research. 35, 1, p. 77-84

    Research output: Contribution to journalArticle

  19. Published

    Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma

    Dr Rhiannon Lloyd, Kathleen Keatley, D. Timothy J. Littlewood, Bridgitte Meunier, William V. Holt, Dr Qian An, Samantha C. Higgins, Stavros Polyzoidis, Katie F. Stephenson, Keyoumars Ashkan & 3 others, Dr Helen Fillmore, Professor Geoff Pilkington & Professor John McGeehan, 2015, In : Neuro-Oncology. p. 1-11

    Research output: Contribution to journalArticle

  20. 2014
  21. Published

    Expression of the chondroitin sulphate proteoglycan, NG2, in paediatric brain tumors

    Samantha Higgins, Anna J. Boltheus, Laura Donovan, Harutomo Hasegawa, Lawrence Doey, Safa Al Sarraj, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, 1 Dec 2014, In : Anticancer Research. 34, 12, p. 6919-6924 6 p.

    Research output: Contribution to journalArticle

  22. Published

    Wilms tumor 1 gene, CD97, and the emerging biogenetic profile of glioblastoma

    Aravind Somasundaram, Nathan Ardanowski, Charles F. Opalak, Dr Helen Fillmore, Archana Chidambaram & William C. Broaddus, 1 Dec 2014, In : Neurosurgical Focus. 37, 6, p. E14

    Research output: Contribution to journalArticle

  23. Published

    Brain tumor cell line authentication, an efficient alternative to capillary electrophoresis by using a microfluidics-based system

    Dr Qian An, Dr Helen Fillmore, Mikaella Vouri & Professor Geoff Pilkington, Jan 2014, In : Neuro-Oncology. 16, 2, p. 265-273

    Research output: Contribution to journalArticle

  24. 2012
  25. Published

    Novel report of expression and function of CD97 in malignant gliomas: correlation with Wilms tumor 1 expression and glioma cell invasiveness

    A. Chidambaram, Dr Helen Fillmore, T. Van Meter, C. Dumur & W. Broaddus, Apr 2012, In : Journal of Neurosurgery. 116, 4, p. 843-853 11 p.

    Research output: Contribution to journalArticle

  26. Published

    Matrix metalloproteinase-1 expression enhances tumorigenicity as well as tumor-related angiogenesis and is inversely associated with TIMP-4 expression in a model of glioblastoma

    N. Pullen, M. Anand, P. Cooper & Dr Helen Fillmore, 2012, In : Journal of Neuro-Oncology. 106, 3, p. 461-471 11 p.

    Research output: Contribution to journalArticle

  27. 2011
  28. Published

    Wilms’ tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression

    M. Chen, A. Clark, D. Chan, J. Ware, S. Holt, A. Chidambaram, Dr Helen Fillmore & W. Broaddus, May 2011, In : Journal of Neuro-Oncology. 103, 1, p. 87-102 16 p.

    Research output: Contribution to journalArticle

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