Dr Helen Fillmore
Reader in Molecular Neuropathology and Neuro-oncology
- 2019
- Published
Human Sialic acid O-acetyl esterase (SIAE) – mediated changes in sensitivity to etoposide in a medulloblastoma cell line
Rebecca L. Mather, Katie Loveson & Dr Helen Fillmore, 13 Jun 2019, In: Scientific Reports. 9, 8609.Research output: Contribution to journal › Article › peer-review
- Early online
Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood–brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis
Samah A. Jassam, Dr Zaynah Maherally, Keyoumars Ashkan, Professor Geoff Pilkington & Dr Helen Fillmore, 18 May 2019, In: Journal of Neuro-Oncology. 11 p.Research output: Contribution to journal › Article › peer-review
- 2018
- Published
Intersection of brain development and paediatric diffuse midline gliomas: potential role of microenvironment in tumour growth
Katie Loveson & Dr Helen Fillmore, 16 Nov 2018, In: Brain Sciences. 8, 11, 200.Research output: Contribution to journal › Article › peer-review
- Published
Current insights into Matrix metalloproteinases and glioma progression: transcending the degradation boundary
N. Pullen, Professor Andrew Pickford, M. M. Perry, D. M. Jaworski, K. Loveson, D. Arthur, J. Holliday, T. Van Meter, R. Peckham, W. Younas & 5 others, , 17 Sep 2018, In: Metalloproteinases in Medicine. 5, p. 13-30Research output: Contribution to journal › Article › peer-review
- Published
Oxamate, but not selective targeting of LDH-A, inhibits medulloblastoma cell glycolysis, growth and motility
Cara Valvona & Dr Helen Fillmore, Apr 2018, In: Brain Sciences. 8, 4, 56.Research output: Contribution to journal › Article › peer-review
- 2017
- Published
Real-time acquisition of transendothelial electrical resistance in an all-human, in vitro, 3-dimensional, blood–brain barrier model exemplifies tight-junction integrity
Dr Zaynah Maherally, Dr Helen Fillmore, Sim Ling Tan, Suk Fei Tan, Samah A. Jassam, Friederike I. Quack, Kathryn E. Hatherell & Professor Geoff Pilkington, Sep 2017, In: FASEB Journal. 32, 1, p. 168-182Research output: Contribution to journal › Article › peer-review
- Published
CD15s/CD62E interaction mediates the adhesion of non-small cell lung cancer cells on brain endothelial cells: implications for cerebral metastasis
Samah Jassam, Dr Zaynah Maherally, Dr James Smith, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, 10 Jul 2017, In: International Journal of Molecular Sciences. 18, 7, 1474.Research output: Contribution to journal › Article › peer-review
- 2016
- Published
TNF-a enhancement of CD62E mediates adhesion of non-small cell lung cancer cells to brain endothelium via CD15 in lung-brain metastasis
Samah Ali Jassam, Dr Zaynah Maherally, Dr James Smith, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, May 2016, In: Neuro-Oncology. 18, 5, p. 679-690 12 p.Research output: Contribution to journal › Article › peer-review
- Published
AFM observation of heightened cell periphery of high-grade glioblastoma cell lines
Dr James Smith, Dr Zaynah Maherally, Samantha C. Higgins, Dr Qian An, Dr Helen Fillmore & Professor Geoff Pilkington, Mar 2016, In: BioNanoScience. 6, 1, p. 47-53Research output: Contribution to journal › Article › peer-review
- Published
Silencing of CD44 in glioma leads to changes in cytoskeletal protein expression and cellular biomechanical deformation properties as measured by AFM nanoindentation
Dr Zaynah Maherally, Dr James Smith, Manar K. Ghoneim, Luke Dickson, Dr Qian An, Dr Helen Fillmore & Professor Geoff Pilkington, Mar 2016, In: BioNanoScience. 6, 1, p. 54-64Research output: Contribution to journal › Article › peer-review
- Published
NSCLC Cell Adhesion to and Transmigration through Brain Endothelium in Brain Metastasis
Samah Ali Jassam, Dr Zaynah Maherally, Dr Helen Fillmore & Professor Geoff Pilkington, Jan 2016, WFNOS Magazine, 1, 1, p. 2-6 5 p.Research output: Contribution to specialist publication › Article
- Published
The regulation and function of Lactate Dehydrogenase A: therapeutic potential in brain tumor
Cara Valvona, Dr Helen Fillmore, Peter Nunn & Professor Geoff Pilkington, Jan 2016, In: Brain Pathology. 26, 1, p. 3-17Research output: Contribution to journal › Article › peer-review
- 2015
- Published
Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma
Dr Rhiannon Lloyd, Kathleen Keatley, D. Timothy J. Littlewood, Bridgitte Meunier, William V. Holt, Dr Qian An, Samantha C. Higgins, Stavros Polyzoidis, Katie F. Stephenson, Keyoumars Ashkan & 3 others, , Jul 2015, In: Neuro-Oncology. 17, p. 1-11Research output: Contribution to journal › Article › peer-review
- Published
Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro
Samantha C. Higgins, Dr Helen Fillmore, Keyoumars Ashkan, Professor Arthur Butt & Professor Geoff Pilkington, Jan 2015, In: Anticancer Research. 35, 1, p. 77-84Research output: Contribution to journal › Article › peer-review
- 2014
- Published
Expression of the chondroitin sulphate proteoglycan, NG2, in paediatric brain tumors
Samantha Higgins, Anna J. Boltheus, Laura Donovan, Harutomo Hasegawa, Lawrence Doey, Safa Al Sarraj, Keyoumars Ashkan, Federico Roncaroli, Dr Helen Fillmore & Professor Geoff Pilkington, 1 Dec 2014, In: Anticancer Research. 34, 12, p. 6919-6924 6 p.Research output: Contribution to journal › Article › peer-review
- Published
Wilms tumor 1 gene, CD97, and the emerging biogenetic profile of glioblastoma
Aravind Somasundaram, Nathan Ardanowski, Charles F. Opalak, Dr Helen Fillmore, Archana Chidambaram & William C. Broaddus, 1 Dec 2014, In: Neurosurgical Focus. 37, 6, p. E14Research output: Contribution to journal › Article › peer-review
- Published
Brain tumor cell line authentication, an efficient alternative to capillary electrophoresis by using a microfluidics-based system
Dr Qian An, Dr Helen Fillmore, Mikaella Vouri & Professor Geoff Pilkington, 1 Feb 2014, In: Neuro-Oncology. 16, 2, p. 265-273Research output: Contribution to journal › Article › peer-review
- 2012
- Published
Novel report of expression and function of CD97 in malignant gliomas: correlation with Wilms tumor 1 expression and glioma cell invasiveness
A. Chidambaram, Dr Helen Fillmore, T. Van Meter, C. Dumur & W. Broaddus, Apr 2012, In: Journal of Neurosurgery. 116, 4, p. 843-853 11 p.Research output: Contribution to journal › Article › peer-review
- Published
Matrix metalloproteinase-1 expression enhances tumorigenicity as well as tumor-related angiogenesis and is inversely associated with TIMP-4 expression in a model of glioblastoma
N. Pullen, M. Anand, P. Cooper & Dr Helen Fillmore, 2012, In: Journal of Neuro-Oncology. 106, 3, p. 461-471 11 p.Research output: Contribution to journal › Article › peer-review
- 2011
- Published
Wilms’ tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression
M. Chen, A. Clark, D. Chan, J. Ware, S. Holt, A. Chidambaram, Dr Helen Fillmore & W. Broaddus, May 2011, In: Journal of Neuro-Oncology. 103, 1, p. 87-102 16 p.Research output: Contribution to journal › Article › peer-review
ID: 19015