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Dr James Brown

Associate Head (Global Engagement and Education Partnerships)

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  1. Early online

    A novel self-assembling peptide for hemostasis during endoscopic submucosal dissection: a randomized controlled trial

    Sharmila Subramaniam, Kesavan Kandiah, Fergus Chedgy, Carole Fogg, Sreedhari Thayalasekaran, Asma Alkandari, Michelle Baker-Moffatt, Joanne Dash, Mark Lyons-Amos, Gaius Longcroft-Wheaton & 2 others, Dr James Brown & Mr Pradeep Bhandari, 17 Jul 2020, In: Endoscopy.

    Research output: Contribution to journal › Article › peer-review

  2. Published

    A randomized controlled trial of pre-procedure simethicone and N-acetylcysteine to improve mucosal visibility during gastroscopy – NICEVIS

    Peter Basford, Dr James Brown, Lisa Gadeke, Carole Fogg, Ben Haysom-Newport, Reuben Ogollah, Rupam Bhattacharyya, Gaius Longcroft-wheaton, Fergus Thursby-Pelham, James Neale & 1 others, Mr Pradeep Bhandari, Nov 2016, In: Endoscopy International Open. 04, 11, p. E1197-E1202

    Research output: Contribution to journal › Article › peer-review

  3. Published

    Active ulcerative colitis is associated with altered fatty acid precursor availability for the eicosanoid synthetic pathway

    D. S. Pearl, D. Gullick, J. Bruemmer, Dr James Brown, Professor Janis Kay Shute, Professor Graham Mills & T. M. Trebble, 1 Apr 2011, In: Gut. 60, Suppl 1, p. A213-A214

    Research output: Contribution to journal › Article › peer-review

  4. Published

    Altered colonic mucosal availability of n-3 and n-6 polyunsaturated fatty acids in ulcerative colitis and the relationship to disease activity

    Daniel S. Pearl, Mojgan Masoodi, Michael Eiden, Janine Brummer, Darren Gullick, Tricia M. Mckeever, Mark A. Whittaker, Harriet Nitch-Smith, Dr James Brown, Professor Janis Kay Shute & 3 others, Professor Graham Mills, Philip C. Calder & Timothy M. Trebble, 1 Jan 2014, In: Journal of Crohn's and Colitis. 8, 1, p. 70-79

    Research output: Contribution to journal › Article › peer-review

  5. Published

    Altered colonic mucosal polyunsaturated fatty acid (PUFA) derived lipid mediators in ulcerative colitis: New insight into relationship with disease activity and pathophysiology

    Mojgan Masoodi, Daniel S. Pearl, Michael Eiden, Professor Janis Kay Shute, Dr James Brown, Philip C. Calder & Timothy M. Trebble, 18 Oct 2013, In: PLoS One. 8, 10, e76532.

    Research output: Contribution to journal › Article › peer-review

  6. Published

    Azo compounds in colon-specific drug delivery

    Dr Marta Roldo, Eugen Barbu, Dr James Brown, Dr David Laight, John D. Smart & Dr John Tsibouklis, Sep 2007, In: Expert Opinion on Drug Delivery. 4, 5, p. 547-560 14 p.

    Research output: Contribution to journal › Article › peer-review

  7. Published

    Bradykinin stimulates PGE2 release in cell fractions isolated from the rat gastric mucosa via a B1 receptor

    Dr James Brown, Brendan J. R. Whittle & P. J. Hanson, 1 Aug 1992, p. 276S. 1 p.

    Research output: Contribution to conference › Paper › peer-review

  8. Early online

    Cannabidiol and cannabigerol inhibit spontaneous contractions in the mouse isolated uterus

    Dr James Brown, Georgieva Teodora, Roshni Rajendran, Brigitte Gyeke, Kirsten Handy & Mohsen Seifi, 13 Apr 2020, In: British Journal of Pharmacology. p. 79-80 2 p., P132.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  9. Published

    Cytokine mucosal expression in ulcerative colitis, the relationship between cytokine release and disease activity

    D. Pearl, K. Shah, M. Whittaker, H. Nitch-Smith, Dr James Brown, Professor Janis Kay Shute & T. Trebble, 1 Jul 2013, In: Journal of Crohn's and Colitis. 7, 6, p. 481-489 9 p.

    Research output: Contribution to journal › Article › peer-review

  10. Published

    Development and validation of a training module on the use of acetic acid for the detection of Barrett's neoplasia

    Fergus Chedgy, Kesavan Kandiah, Hugh Barr, John De Caestecker, Simon Dwerryhouse, Balint Eross, Charles Gordon, Susi Green, Andy Li, Dr James Brown & 2 others, Gaius Longcroft-Wheaton & Mr Pradeep Bhandari, 1 Feb 2017, In: Endoscopy. 49, 02, p. 121-129 9 p.

    Research output: Contribution to journal › Article › peer-review

  11. Published

    Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa

    Dr James Brown, B. L. Tepperman, P. J. Hanson, B. J. R. Whittle & S. Moncada, 30 Apr 1992, In: Biochemical and Biophysical Research Communications. 184, 2, p. 680-685 6 p.

    Research output: Contribution to journal › Article › peer-review

  12. Published

    Duration of acetowhitening as a novel objective tool for diagnosing high risk neoplasia in Barrett’s esophagus: a prospective cohort trial

    Gaius Longcroft-Wheaton, Dr James Brown, P. Basford, D. Cowlishaw, Bernard Higgins & Mr Pradeep Bhandari, 3 Jun 2013, In: Endoscopy. 45, 6, p. 426-432 7 p.

    Research output: Contribution to journal › Article › peer-review

  13. Early online

    Effects of cannabidiol and cannabigerol on isolated intestinal smooth muscle

    Dr James Brown, Amasha Bellange, Bernadette Dwimoh, Fateha Asha, Neamatullah Niazi & Siman Patel, 13 Apr 2020, In: British Journal of Pharmacology. p. 80-81 2 p., P133.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  14. Published

    Endoscopic characterization of small colonic polyps: baseline performance of experienced endoscopists is no different to that of medical students

    Peter Basford, Dr James Brown, Sarah Cooper & Mr Pradeep Bhandari, 1 Apr 2019, In: Endoscopy International Open. 7, 4, p. E403-E411 9 p.

    Research output: Contribution to journal › Article › peer-review

  15. Published

    Functional and pharmacological characterisation of potassium channel subtypes in the mouse intestine

    Dr Ruolin Ma, Dr James Brown & Dr Anthony Lewis, 2015, Proceedings of the British Pharmacological Society: pA2 online. 3 ed. Vol. 13. 1 p. 293P

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  16. Published

    Gastric mucosal nitric oxide synthase activity inhibition by phosphorylation, arginine analogues and trifluoperazine

    J. M. Williams, Dr James Brown, P. J. Hanson & B. J. R. Whittle, 1 Aug 1994, p. 271S. 1 p.

    Research output: Contribution to conference › Paper › peer-review

  17. Published

    High-definition vs. standard-definition colonoscopy in the characterization of small colonic polyps: results from a randomized trial

    Gaius Longcroft-Wheaton, Dr James Brown, D. Cowlishaw, Bernard Higgins & Mr Pradeep Bhandari, Oct 2012, In: Endoscopy. 44, 10, p. 905-910 6 p.

    Research output: Contribution to journal › Article › peer-review

  18. Published

    High-definition vs. standard-definition endoscopy with indigo carmine for the in vivo diagnosis of colonic polyps

    Gaius Longcroft-Wheaton, Dr James Brown, David Cowlishaw, Bernard Higgins & Mr Pradeep Bhandari, Dec 2013, In: United European Gastroenterology Journal. 16, 1, p. 425-429

    Research output: Contribution to journal › Article › peer-review

  19. Published

    Increased susceptibility to ATP via alteration of P2X receptor function in dystrophic mdx mouse muscle cells

    Davy Yeung, Krzysztof Zablocki, Chun-Fu Lien, Taiwen Jiang, Stephen Arkle, Wojciech Brutkowski, Dr James Brown, Hanns Lochmuller, Joseph Simon, Eric A. Barnard & 1 others, Professor Darek Gorecki, Apr 2006, In: FASEB Journal. 20, 6, p. 610-620

    Research output: Contribution to journal › Article › peer-review

  20. Published

    Lipopolysaccharide induces Ca2+-independent nitric oxide synthase activity in rat gastric mucosal cells

    Dr James Brown, Barry L. Tepperman, Peter J. Hanson & Brendan J. R. Whittle, 1 Nov 1994, In: European Journal of Pharmacology: Environmental Toxicology and Pharmacology. 292, 1, p. 111-114 4 p.

    Research output: Contribution to journal › Article › peer-review

  21. Published

    Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse Colon

    Mohsen Seifi, Dr James Brown, Dr Jeremy Mills, Mr Pradeep Bhandari, Delia Belelli, Jeremy J. Lambert, Uwe Rudolph & Professor Jerome Swinny, 30 Jul 2014, In: Journal of Neuroscience. 34, 31, p. 10361-10378 18 p.

    Research output: Contribution to journal › Article › peer-review

  22. Published

    Molecular and pharmacological characterisation of mechano-gated K-2P channels in the mouse gastrointestinal tract

    Dr Ruolin Ma, Mohsen Seifi, Dr Maria Papanikolaou, Professor Jerome Swinny, Dr James Brown & Dr Anthony Lewis, 1 Apr 2017, In: FASEB Journal. 31, 1_supplement, 1047.3.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  23. Early online

    Multicentre randomised controlled trial on virtual chromoendoscopy in the detection of neoplasia during colitis surveillance high-definition colonoscopy (the VIRTUOSO trial)

    Kesavan Kandiah, Sharmila Subramaniam, Sreedhari Thayalasekaran, Fergus Chedgy, Gaius Longcroft-Wheaton, Carole Fogg, Dr James Brown, Samuel Smith, Marietta Iacucci & Mr Pradeep Bhandari, 19 Nov 2020, In: Gut.

    Research output: Contribution to journal › Article › peer-review

  24. Published

    Nitric oxide donors increase mucus gel thickness in rat stomach

    Dr James Brown, Peter J. Hanson & Brendan J. R. Whittle, 13 Nov 1992, In: European Journal of Pharmacology. 223, 1, p. 103-104 2 p.

    Research output: Contribution to journal › Article › peer-review

  25. Published

    Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells

    Dr James Brown, A. C. Keates, P. J. Hanson & B. J. R. Whittle, 1 Sep 1993, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 265, 3, p. G418-G422 5 p.

    Research output: Contribution to journal › Article › peer-review

  26. Published

    Nitric oxide synthase activity in collagenase digests of rat small intestinal muscle can be resolved from the muscle cells on a Percoll gradient

    S. Garcia, Dr James Brown & P. J. Hanson, 1 Aug 1994, p. 270S. 1 p.

    Research output: Contribution to conference › Paper › peer-review

  27. Published

    Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge

    B. L. Tepperman, Dr James Brown, R. Korolkiewicz & Brendan J. R. Whittle, 1 Dec 1994, In: Journal of Pharmacology and Experimental Therapeutics. 271, 3, p. 1477-1482 6 p.

    Research output: Contribution to journal › Article › peer-review

  28. Published

    Nitric oxide synthase and arginase in cells isolated from the rat gastric mucosa

    Clare R. Byrne, Kenneth J. Price, Julie M. Williams, Dr James Brown, Peter J. Hanson & Brendan J. R. Whittle, 24 Apr 1997, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1356, 2, p. 131-139 9 p.

    Research output: Contribution to journal › Article › peer-review

  29. Published

    Nitric oxide synthase induction and intestinal epithelial cell viability in rats

    B. L. Tepperman, Dr James Brown & Brendan J. R. Whittle, 1 Aug 1993, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 265, 2, p. G214-G218 5 p.

    Research output: Contribution to journal › Article › peer-review

  30. Published

    Ontogeny of nitric oxide synthase activity and endotoxin-mediated damage in the neonatal rat colon

    Dr James Brown & B. L. Tepperman, 1 May 1997, In: Pediatric Research. 41, 5, p. 635-640 6 p.

    Research output: Contribution to journal › Article › peer-review

  31. Published

    Orally administered, colon-specific mucoadhesive azopolymer particles for the treatment of inflammatory bowel disease: an in vivo study

    Dr Marta Roldo, Eugen Barbu, Dr James Brown, Dr David Laight, J. Smart & Dr John Tsibouklis, 2006, In: Journal of Biomedical Materials Research Part A. 79A, 3, p. 706-715 10 p.

    Research output: Contribution to journal › Article › peer-review

  32. Published

    Protein kinase C mediates experimental colitis in the rat

    Dr James Brown, Qing Chang, Brian D. Soper & Barry L. Tepperman, 1 Mar 1999, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 276, 3, p. G583-G590 8 p.

    Research output: Contribution to journal › Article › peer-review

  33. Early online

    Recovery of endoscopy services in the era of COVID-19: recommendations from an international Delphi consensus

    Mr Pradeep Bhandari, Sharmila Subramaniam, Michael J. Bourke, Asma Alkandari, Philip Wai Yan Chiu, Dr James Brown, Rajesh N. Keswani, Raf Bisschops, Cesare Hassan, Gottumukkala S. Raju & 28 others, V. Raman Muthusamy, Amrita Sethi, Gary R. May, Eduardo Albéniz, Marco Bruno, Michal Filip Kaminski, Maryam Alkhatry, Majid Almadi, Mostafa Ibrahim, Fabian Emura, Eduardo Moura, Claudio Navarrete, Adolfo Wulfson, Christopher Khor, Ryan Ponnudurai, Haruhiro Inoue, Yutaka Saito, Naohisa Yahagi, Sergey Kashin, Evgeniy Nikonov, Honggang Yu, Amit P. Maydeo, D. Nageshwar Reddy, Michael B. Wallace, Mark Bennett Pochapin, Thomas Rösch, Prateek Sharma & Alessandro Repici, 14 Aug 2020, In: Gut. 10 p.

    Research output: Contribution to journal › Article › peer-review

  34. Published

    Relaxant effects of parathyroid hormone and parathyroid hormone-related peptides on oviduct motility in birds and mammals: possible role of nitric oxide

    M. Francis, M. Arkle, L. Martin, T. M. Butler, M. C. Cruz, G. Opare-Aryee, C. G. Dacke & Dr James Brown, 1 Sep 2003, In: General and Comparative Endocrinology. 133, 2, p. 243-251 9 p.

    Research output: Contribution to journal › Article › peer-review

  35. Published

    Role of mast cells, neutrophils and nitric oxide in endotoxin-induced damage to the neonatal rat colon

    Dr James Brown, K. A. Chafee & B. L. Tepperman, 1 Jan 1998, In: British Journal of Pharmacology. 123, 1, p. 31-38 8 p.

    Research output: Contribution to journal › Article › peer-review

  36. Published

    Role of nitric oxide in hypoxia-induced colonic dysfunction in the neonatal rat

    Dr James Brown & Barry L. Tepperman, 1 Apr 1997, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 4, p. G760-G769 10 p.

    Research output: Contribution to journal › Article › peer-review

  37. Published

    Sa1458 Nicevis: results of a randomised controlled trial of simeticone and n-acetylcysteine as a pre-procedure drink to Improve mucosal visibility during diagnostic gastroscopy

    Peter Basford, Dr James Brown, Lisa Gadeke, Carole Lesley Fogg, Ben Haysom-Newport, Reuben Ogollah, Bernard Robert Higgins, Rupam Bhattacharyya, Gaius Longcroft-Wheaton, Fergus Thursby-Pelham & 2 others, Jo Neale & Mr Pradeep Bhandari, May 2015, In: Gastrointestinal Endoscopy. 81, 5 supp, p. ab224

    Research output: Contribution to journal › Meeting Abstract › peer-review

  38. Published

    TREK-1 channel expression in smooth muscle as a target for regulating murine intestinal contractility: therapeutic implications for motility disorders

    Dr Ruolin Ma, Mohsen Seifi, Dr Maria Papanikolaou, Dr James Brown, Professor Jerome Swinny & Dr Anthony Lewis, 6 Mar 2018, In: Frontiers in Physiology. 9, 157.

    Research output: Contribution to journal › Article › peer-review

  39. Published

    The effect of protein kinase C activation on colonic epithelial cellular integrity

    Barry L. Tepperman, Brian D. Soper, Qing Chang, Dr James Brown & Candice A. Wakulich, 18 Feb 2000, In: European Journal of Pharmacology. 389, 2-3, p. 131-140 10 p.

    Research output: Contribution to journal › Article › peer-review

  40. Published

    The nitric oxide donor, S-nitroso-N-acetyl-penicillamine, inhibits secretory activity in rat isolated parietal cells

    Dr James Brown, P. J. Hanson & B. J. R. Whittle, 30 Sep 1993, In: Biochemical and Biophysical Research Communications. 195, 3, p. 1354-1359 6 p.

    Research output: Contribution to journal › Article › peer-review

ID: 25444