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Professor John McGeehan

Professor of Structural Biology

  1. 2013
  2. Published

    Structural characterization of a unique marine animal family 7 cellobiohydrolase suggests a mechanism of cellulase salt tolerance

    M. Kern, Professor John McGeehan, Simon Streeter, Richard Martin, K. Besser, L. Elias, W. Eborall, Dr Graham Paul Malyon, C. Payne, M. Himmel & 5 others, K. Schnorr, G. Beckham, Professor Simon Cragg, N. Bruce & S. McQueen-Mason, 18 Jun 2013, In: Proceedings of the National Academy of Sciences. 110, 25, p. 10189-10194 6 p.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Non-rigid image registration to reduce beam-induced blurring of cryo-electron microscopy images

    F. Karimi Nejadasl, M. Karuppasamy, E. Newman, Professor John McGeehan & R. Ravelli, 1 Jan 2013, In: Journal of Synchrotron Radiation. 20, 1

    Research output: Contribution to journalArticlepeer-review

  4. 2012
  5. Published

    Recognition of dual symmetry by the controller protein C.Esp1396I based on the structure of the transcriptional activation complex

    Professor John McGeehan, Neil J. Ball, Simon Streeter, Sarah Thresh & Geoff Kneale, 30 Dec 2012, In: Nucleic Acids Research. 40, 9, p. 4158-4167 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Large multimeric assemblies of nucleosome assembly protein and histones revealed by small-angle X-ray scattering and electron microscopy

    E. Newman, Geoff Kneale, R. Ravelli, M. Karuppasamy, F. Nejadasl, I. Taylor & Professor John McGeehan, 2012, In: The Journal of Biological Chemistry. 287, 32, p. 26657-26665 9 p.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    The structural basis of differential DNA sequence recognition by restriction–modification controller proteins

    Neil J. Ball, Professor John McGeehan, Simon Streeter, Sarah Thresh & Geoff Kneale, 2012, In: Nucleic Acids Research. 40, 20, p. 10532-10542 11 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2011
  9. Published

    Amyloid- 42 interacts mainly with insoluble prion protein in the Alzheimer brain

    Wen-Quan Zou, Xiangzhu Xiao, Jue Yuan, Gianfranco Puoti, Hisashi Fujioka, Xinglong Wang, Sandy Richardson, Xiaochen Zhou, Roger Zou, Shihao Li & 10 others, Xiongwei Zhu, Patrick L. McGeer, Professor John McGeehan, Geoff Kneale, Diego E. Rincon-Limas, Pedro Fernandez-Funez, Hyoung-Gon Lee, Mark A. Smith, Robert B. Petersen & Jian-Ping Guo, 29 Apr 2011, In: The Journal of Biological Chemistry. 286, 17, p. 15095-15105

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Infrared protein crystallography

    J. Timothy Sage, Yunbin Zhang, Professor John McGeehan, Raimond B. G. Ravelli, Martin Weik & Jasper J. Van Thor, 2011, In: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics. 1814, 6, p. 760-777 18 p.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Size does matter: sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action

    John Spencer, Jahangir Amin, Dr Peter Coxhead, Professor John McGeehan, Christopher J. Richards, Graham J. Tizzard, Simon J. Coles, John P. Bingham, John A. Hartley, Li Feng & 2 others, Eric Meggers & Professor Matt Guille, 2011, In: Organometallics. 30, 11, p. 3177-3181

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Structural analysis of a novel class of R-M controller proteins: C.Csp231I from Citrobacter sp. RFL231

    Professor John McGeehan, Simon Streeter, Sarah Thresh, J. Taylor, Misha Shevtsov & Geoff Kneale, 2011, In: Journal of Molecular Biology. 409, 2, p. 177-188 12 p.

    Research output: Contribution to journalArticlepeer-review

  13. 2010
  14. Published

    Reply to Kascsak: definition of the PrP 3F4 epitope revisited

    W. Zou, J. Langeveld, X. Xiao, S. Chen, P. McGeer, J. Yuan, M. Payne, H. Kang, Professor John McGeehan, M. Sy & 10 others, N. Greenspan, D. Kaplan, G. Wang, P. Parchi, E. Hoover, Geoff Kneale, G. Telling, W. Surewicz, Q. Kong & J. Guo, 14 May 2010, In: The Journal of Biological Chemistry. 285, 20, p. le6-le6

    Research output: Contribution to journalArticle

  15. Published

    PrP conformational transitions alter species preference of a PrP-specific antibody

    Wen-Quan Zou, Jan Langeveld, Xiangzhu Xiao, Shugui Chen, P. L. Mcgeer, Jue Yuan, Michael C. Payne, Hae-Eun Kang, Professor John McGeehan, Man-Sun Sy & 10 others, Neil S. Greenspan, David Kaplan, Gong-Xian Wang, Piero Parchi, Edward Hoover, Geoff Kneale, Glenn Telling, Witold K. Surewicz, Qingzhong Kong & Jian-Ping Guo, 30 Apr 2010, In: The Journal of Biological Chemistry. 285, 18, p. 13874-13884

    Research output: Contribution to journalArticlepeer-review

  16. Published

    New insights from NMR, FTIR, X-ray diffraction and physical chemistry into digestive processes in the wood-boring marine crustacean Limnoria quadripunctata

    Dr Graham Paul Malyon, S. LaBarre, N. Kervarec, Peter Cary, Professor John McGeehan, X. Xie, A. Kluppel & Professor Simon Cragg, 2010, p. 1-16. 16 p.

    Research output: Contribution to conferencePaperpeer-review

  17. Published

    Raman-assisted crystallography of biomolecules at the synchrotron: Instrumentation, methods and applications

    Professor John McGeehan, D. Bourgeois, A. Royant & P. Carpentier, 2010, In: Biochimica et Biophysica Acta. 1814, 6, p. 750-759 10 p.

    Research output: Contribution to journalArticlepeer-review

  18. 2009
  19. Published

    Failure to detect the presence of prions in the uterine and gestational tissues from a gravida with Creutzfeldt-Jakob disease

    Xiangzhu Xiao, Leticia Miravalle, Jue Yuan, Professor John McGeehan, Zhigian Dong, Robert Wyza, Gregory T. MacLennan, Alan M. Golichowski, Geoff Kneale, Nicholas King & 7 others, Qingzhong Kong, Salvatore Spina, Ruben Vidal, Bernardino Ghetti, Karen Roos, Pierluigi Gambetti & Wen-Quan Zou, May 2009, In: American Journal of Pathology. 174, 5, p. 1602-1608

    Research output: Contribution to journalArticlepeer-review

  20. Published

    Colouring cryo-cooled crystals: on-line microspectrophotometry

    Professor John McGeehan, R. Ravelli, J. W. Murray, Robin Leslie Owen, F. Cipriani, S. McSweeney, M. Weik & E. Garman, 2009, In: Journal of Synchrotron Radiation. 16, p. 163-172 10 p.

    Research output: Contribution to journalArticlepeer-review

  21. Published

    Overexpression, purification and preliminary X-ray diffraction analysis of the controller protein C.Csp231I from Citrobacter sp. RFL231

    Simon Streeter, Professor John McGeehan & Geoff Kneale, 2009, In: Acta Crystallographica - Section F. F65, Pt 9, p. 898-901 4 p.

    Research output: Contribution to journalArticlepeer-review

  22. Published

    Structural and biophysical characterization of the proteins interacting with the herpes simplex virus-1 origin of replication

    I. Manolaridis, E. Mumtsidu, P. Konarev, A. Makhov, S. Fullerton, A. Sinz, S. Kalkhof, Professor John McGeehan, Peter Cary, J. Griffith & 3 others, D. Svergun, Geoff Kneale & P. Tucker, 2009, In: The Journal of Biological Chemistry. 284, 24, p. 16343-16353 11 p.

    Research output: Contribution to journalArticlepeer-review

  23. Published

    Structure of the restriction-modification controller protein C.Esp1396I

    Neil J. Ball, Simon Streeter, Geoff Kneale & Professor John McGeehan, 2009, In: Acta Crystallographica Section D Biological Crystallography. D65, p. 900-905 6 p.

    Research output: Contribution to journalArticlepeer-review

  24. Published

    X-ray tomography on MX samples

    S. Brockhauser, A. McCarthy, M. Di Michiel & Professor John McGeehan, 2009, p. S166.

    Research output: Contribution to conferencePaperpeer-review

  25. 2008
  26. Published

    Accessibility of a critical prion protein region involved in strain recognition and its implications for the early detection of prions

    J. Yuan, Z. Dong, J. Guo, Professor John McGeehan, X. Xiao, J. Wang, I. Cali, P. McGeer, N. Cashman, R. Bessen & 5 others, W. Surewicz, Geoff Kneale, R. Petersen, P. Gambetti & Wen-Quan Zou, 2008, In: Cellular and Molecular Life Sciences (CMLS). 65, 4, p. 631-643 13 p.

    Research output: Contribution to journalArticlepeer-review

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