Dr John Tsibouklis

Biomaterials with inherent resistance to bacterial colonisation, Bioadhesion/mucoadhesion, Surface Science Research, Colonic drug delivery, Ocular drug delivery, Boron neutron-capture therapy.

For more information about my research please visit my lab page.

• Controlled and targeted drug delivery: design and development of specific retentive delivery systems aimed at mucosal surfaces; nanomaterials for the transport of chemotherapeutant; stimuli-responsive polymer conjugates for the release of therapeutic agents.
• Low-surface-energy materials: synthesis, surface characterisation of polymeric materials with ultra-low-surface-energy characteristics.
• Bioadhesion/mucoadhesion: bioadhesive materials for therapeutic use in the eye, mouth, stomach and colon.
• Biomolecular recognition: receptor molecules with potential applications as either binding agents or controlled release systems; support matrices for in vitro toxicology.
• Bioadhesion control: development of materials that inhibit bacterial binding to biological surfaces and biomaterials; use of responsive ('smart') polymers displaying hydrophilic-hydrophobic transitions.
• Therapeutic agents for targeting cancer tumours: boronated cages for cancer therapy; delivery vehicles for the transport of chemotherapeutants across the blood-brain barrier.
• Surface science research: the use of contact angle goniometry, atomic force microscopy, X-ray photoelectron spectroscopy, infrared spectroscopy and other techniques as means of quantifying surface heterogeneity.