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Dr Karen Ball

Head of School

  1. 2019
  2. Published

    ROS as a novel indicator to predict anticancer drug efficacy

    Tarek Zaidieh, Dr James Smith, Dr Karen E. Ball & Dr Qian An, 16 Dec 2019, In: BMC Cancer. 19, 14 p., 1224.

    Research output: Contribution to journalArticlepeer-review

  3. 2013
  4. Published

    Chemical and physical compatibility of continuous intravenous drug infusion combinations used in paediatric intensive care

    Caroline Cole, Andy Fox, Dr Marisa Van Der Merwe, Luke Dickson, Dr Karen E. Ball, Amanda Bevan, Adam Hocking & John Pappachan, 19 Mar 2013, In: Critical Care. 17, 2, p. P383

    Research output: Contribution to journalMeeting Abstractpeer-review

  5. 2008
  6. Published

    4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer

    Paul A. Brough, Wynne Aherne, Xavier Barril, Jenifer Borgognoni, Kathy Boxall, Julie E. Cansfield, Kwai-Ming J. Cheung, Ian Collins, Nicholas G. M. Davies, Martin J Drysdale & 27 others, Brian Dymock, Suzanne A. Eccles, Harry Finch, Alexandra Fink, Angela Hayes, Robert Howes, Roderick E. Hubbard, Dr Karen E. Ball, Allan M. Jordan, Andrea Lockie, Vanessa Martins, Andrew Massey, Thomas P. Matthews, Edward McDonald, Christopher J. Northfield, Laurence H. Pearl, Chrisostomos Prodromou, Stuart Ray, Florence I. Raynaud, Stephen D. Roughley, Swee Y. Sharp, Allan Surgenor, D. Lee Walmsley, Paul Webb, Mike Wood, Paul Workman & Lisa Wright, 24 Jan 2008, In: Journal of Medicinal Chemistry. 51, 2, p. 196-218

    Research output: Contribution to journalArticlepeer-review

  7. 2007
  8. Published

    Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues

    Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Marissa V. Powers, Joanna L. Holmes, Gary Box, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Dr Karen E. Ball & 18 others, Angela Hayes, Anthea Hardcastle, Brian Dymock, Paul A. Brough, Xavier Barril, Julie E. Cansfield, Lisa Wright, Allan Surgenor, Nicolas Foloppe, Roderick E. Hubbard, Wynne Aherne, Laurence Pearl, Keith Jones, Edward McDonald, Florence Raynaud, Sue Eccles, Martin Drysdale & Paul Workman, Apr 2007, In: Molecular Cancer Therapeutics. 6, 4, p. 1198-1211

    Research output: Contribution to journalArticlepeer-review

  9. Published

    In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors

    Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Christomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson & 12 others, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Dr Karen E. Ball, Angela Hayes, Florence Raynaud, Richard Marais, Laurence Pearl, Sue Eccles, Wynne Aherne, Edward Mcdonald & Paul Workman, 1 Mar 2007, In: Cancer Research. 67, 5, p. 2206-2216

    Research output: Contribution to journalArticlepeer-review

  10. 2006
  11. Published

    A fluorescence polarization assay for inhibitors of Hsp90

    R. Howes, Xavier Barril, Brian Dymock, Katherine Grant, C. J. Northfield, A. G. S. Robertson, Allan Surgenor, J. Wayne, Lisa Wright, Dr Karen E. Ball & 5 others, Thomas P. Matthews, K.-M. Cheung, E. MacDonald, Paul Workman & Martin J. Drysdale, 15 Mar 2006, In: Analytical Biochemistry. 350, 2, p. 202-213

    Research output: Contribution to journalArticlepeer-review

  12. 2005
  13. Published

    The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors

    Kwai-Ming J. Cheung, Thomas P. Matthews, Dr Karen E. Ball, Martin Rowlands, Kathy Boxall, Swee Sharp, Alison Maloney, S. Mark Roe, Chrisostomos Prodromou, Laurence Pearl & 3 others, Wynne Aherne, Edward MacDonald & Paul Workman, 15 Jul 2005, In: Bioorganic & Medicinal Chemistry Letters. 15, 14, p. 3338-3343

    Research output: Contribution to journalArticlepeer-review

  14. 2004
  15. Published

    Mechanism of action of a novel series of inhibitors of the Hsp90 molecular chaperone

    Swee Sharp, Alison Maloney, Paul A. Clarke, Wynne Aherne, Suzanne Eccles, Kathy Boxall, Martin Rowlands, Florence Raynaud, Bernard Nutley, Nicola Smith & 10 others, Angela Hayes, Anthea Hardcastle, Laurence Pearl, Christomos Prodromou, Dr Karen E. Ball, Jack Cheung, Thomas P. Matthews, Edward MacDonald, Martin Drysdale & Paul Workman, 2004, In: Proceedings of the American Association for Cancer Research. 45

    Research output: Contribution to journalArticlepeer-review

  16. Published

    The identification of novel Hsp90 inhibitors

    Wynne Aherne, J. Cheung, Dr Karen E. Ball, T. Matthews, T. McDonald, Laurence Pearl, Chrisostomos Prodromou, M. Roe, Martin Rowlands & S. Sharp, 2004, In: Drugs of the Future. 29, Supp A, p. 229

    Research output: Contribution to journalArticlepeer-review

  17. 2003
  18. Published

    Pharmacokinetic and metabolism studies of a novel synthetic series of heat shock protein 90 (Hsp90) inhibitors

    N. Smith, Angela Hayes, Dr Karen E. Ball, T. Matthews, Bernard Nutley, T. McDonald, B. Dymock, Martin Drysdale, Florence Raynaud & Paul Workman, 1 Dec 2003, In: Clinical Cancer Research. 9, 16, p. 6258S

    Research output: Contribution to journalArticlepeer-review

  19. Published

    Structure-activity relationship determination within a group of substituted phenyl sulfamate based compounds against the enzyme oestrone sulfatase

    Chirag Patel, A. Galisson, Dr Karen E. Ball, C. Owen & S. Ahmed, Feb 2003, In: Journal of Pharmacy and Pharmacology. 55, 2, p. 211-218 8 p.

    Research output: Contribution to journalArticlepeer-review

  20. Published

    Synthesis and biochemical evaluation of some novel benzoic acid based esters as potential inhibitors of oestrone sulphatase

    C. Owen, Dr Karen E. Ball, L. Sampson & S. Ahmed, 2003, In: Journal of Pharmacy and Pharmacology. 55, 1, p. 85-93 9 p.

    Research output: Contribution to journalArticlepeer-review

ID: 25588