Dr Karen Ball
Head of School
- 2019
- Published
ROS as a novel indicator to predict anticancer drug efficacy
Tarek Zaidieh, Dr James Smith, Dr Karen E. Ball & Dr Qian An, 16 Dec 2019, In: BMC Cancer. 19, 14 p., 1224.Research output: Contribution to journal › Article › peer-review
- 2013
- Published
Chemical and physical compatibility of continuous intravenous drug infusion combinations used in paediatric intensive care
Caroline Cole, Andy Fox, Dr Marisa Van Der Merwe, Luke Dickson, Dr Karen E. Ball, Amanda Bevan, Adam Hocking & John Pappachan, 19 Mar 2013, In: Critical Care. 17, 2, p. P383Research output: Contribution to journal › Meeting Abstract › peer-review
- 2008
- Published
4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer
Paul A. Brough, Wynne Aherne, Xavier Barril, Jenifer Borgognoni, Kathy Boxall, Julie E. Cansfield, Kwai-Ming J. Cheung, Ian Collins, Nicholas G. M. Davies, Martin J Drysdale & 27 others, , 24 Jan 2008, In: Journal of Medicinal Chemistry. 51, 2, p. 196-218Research output: Contribution to journal › Article › peer-review
- 2007
- Published
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues
Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Marissa V. Powers, Joanna L. Holmes, Gary Box, Thomas P. Matthews, Kwai-Ming J. Cheung, Andrew Kalusa, Dr Karen E. Ball & 18 others, , Apr 2007, In: Molecular Cancer Therapeutics. 6, 4, p. 1198-1211Research output: Contribution to journal › Article › peer-review
- Published
In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors
Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Christomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson & 12 others, , 1 Mar 2007, In: Cancer Research. 67, 5, p. 2206-2216Research output: Contribution to journal › Article › peer-review
- 2006
- Published
A fluorescence polarization assay for inhibitors of Hsp90
R. Howes, Xavier Barril, Brian Dymock, Katherine Grant, C. J. Northfield, A. G. S. Robertson, Allan Surgenor, J. Wayne, Lisa Wright, Dr Karen E. Ball & 5 others, , 15 Mar 2006, In: Analytical Biochemistry. 350, 2, p. 202-213Research output: Contribution to journal › Article › peer-review
- 2005
- Published
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
Kwai-Ming J. Cheung, Thomas P. Matthews, Dr Karen E. Ball, Martin Rowlands, Kathy Boxall, Swee Sharp, Alison Maloney, S. Mark Roe, Chrisostomos Prodromou, Laurence Pearl & 3 others, , 15 Jul 2005, In: Bioorganic & Medicinal Chemistry Letters. 15, 14, p. 3338-3343Research output: Contribution to journal › Article › peer-review
- 2004
- Published
Mechanism of action of a novel series of inhibitors of the Hsp90 molecular chaperone
Swee Sharp, Alison Maloney, Paul A. Clarke, Wynne Aherne, Suzanne Eccles, Kathy Boxall, Martin Rowlands, Florence Raynaud, Bernard Nutley, Nicola Smith & 10 others, , 2004, In: Proceedings of the American Association for Cancer Research. 45Research output: Contribution to journal › Article › peer-review
- Published
The identification of novel Hsp90 inhibitors
Wynne Aherne, J. Cheung, Dr Karen E. Ball, T. Matthews, T. McDonald, Laurence Pearl, Chrisostomos Prodromou, M. Roe, Martin Rowlands & S. Sharp, 2004, In: Drugs of the Future. 29, Supp A, p. 229Research output: Contribution to journal › Article › peer-review
- 2003
- Published
Pharmacokinetic and metabolism studies of a novel synthetic series of heat shock protein 90 (Hsp90) inhibitors
N. Smith, Angela Hayes, Dr Karen E. Ball, T. Matthews, Bernard Nutley, T. McDonald, B. Dymock, Martin Drysdale, Florence Raynaud & Paul Workman, 1 Dec 2003, In: Clinical Cancer Research. 9, 16, p. 6258SResearch output: Contribution to journal › Article › peer-review
- Published
Structure-activity relationship determination within a group of substituted phenyl sulfamate based compounds against the enzyme oestrone sulfatase
Chirag Patel, A. Galisson, Dr Karen E. Ball, C. Owen & S. Ahmed, Feb 2003, In: Journal of Pharmacy and Pharmacology. 55, 2, p. 211-218 8 p.Research output: Contribution to journal › Article › peer-review
- Published
Synthesis and biochemical evaluation of some novel benzoic acid based esters as potential inhibitors of oestrone sulphatase
C. Owen, Dr Karen E. Ball, L. Sampson & S. Ahmed, 2003, In: Journal of Pharmacy and Pharmacology. 55, 1, p. 85-93 9 p.Research output: Contribution to journal › Article › peer-review
ID: 25588