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Dr Michael Zahn

Senior Research Fellow

  1. 2019
  2. Early online

    Chimeric peptidomimetic antibiotics against Gram-negative bacteria

    Anatol Luther, Matthias Urfer, Dr Michael Zahn, Maik Müller, Shuang-Yan Wang, Milon Mondal, Alessandra Vitale, Jean-baptiste Hartmann, Timothy Sharpe, Fabio Lo Monte & 33 others, Harsha Kocherla, Elizabeth Cline, Gabriella Pessi, Parthasarathi Rath, Seyed Majed Modaresi, Petra Chiquet, Sarah Stiegeler, Carolin Verbree, Tobias Remus, Michel Schmitt, Caroline Kolopp, Marie-Anne Westwood, Nicolas Desjonquères, Emile Brabet, Sophie Hell, Karen Lepoupon, Annie Vermeulen, Régis Jaisson, Virginie Rithié, Grégory Upert, Alexander Lederer, Peter Zbinden, Achim Wach, Kerstin Moehle, Katja Zerbe, Hans H. Locher, Francesca Bernardini, Glenn E. Dale, Leo Eberl, Bernd Wollscheid, Sebastian Hiller, John A. Robinson & Daniel Obrecht, 23 Oct 2019, In : Nature.

    Research output: Contribution to journalArticle

  3. Published

    Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach

    Hundeep Kaur, Jean-Baptiste Hartmann, Roman P. Jakob, Dr Michael Zahn, Iwan Zimmermann, Timm Maier, Markus A. Seeger & Sebastian Hiller, 1 Jul 2019, In : Journal of Biomolecular Screening. 73, 6-7, p. 375-384 10 p.

    Research output: Contribution to journalArticle

  4. Published

    Structures of 2-hydroxyisobutyric acid-CoA ligase reveal determinants of substrate specificity and describe a multi-conformational catalytic cycle

    Dr Michael Zahn, Nadya Kurteva-Yaneva, Judith Schuster, Ulrike Krug, Tina Georgi, Roland H. Müller, Thore Rohwerder & Norbert Sträter, 1 Jul 2019, In : Journal of Molecular Biology. 431, 15, p. 2747-2761

    Research output: Contribution to journalArticle

  5. Published

    A multidisciplinary approach toward identification of antibiotic scaffolds for Acinetobacter baumannii

    Satya Prathyusha Bhamidimarri, Dr Michael Zahn, Jigneshkumar Dahyabhai Prajapati, Christian Schleberger, Sandra Söderholm, Jennifer Hoover, Josh West, Ulrich Kleinekathöfer, Dirk Bumann, Mathias Winterhalter & 1 others, Bert Van Den Berg, 1 Feb 2019, In : Structure. 27, 2, p. 268-280.e6

    Research output: Contribution to journalArticle

  6. 2018
  7. Published

    Structural basis for chitin acquisition by marine Vibrio species

    Anuwat Aunkham, Dr Michael Zahn, Anusha Kesireddy, Karunakar Reddy Pothula, Albert Schulte, Arnaud Baslé, Ulrich Kleinekathöfer, Wipa Suginta & Bert van den Berg, 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 220.

    Research output: Contribution to journalArticle

  8. Published

    Getting drugs into gram-negative bacteria: rational rules for permeation through general porins

    Silvia Acosta-gutiérrez, Luana Ferrara, Monisha Pathania, Muriel Masi, Jiajun Wang, Igor Bodrenko, Dr Michael Zahn, Mathias Winterhalter, Robert A. Stavenger, Jean-Marie Pagès & 4 others, James H. Naismith, Bert van den Berg, Malcolm G. P. Page & Matteo Ceccarelli, 12 Oct 2018, In : ACS Infectious Diseases. 4, 10, p. 1487-1498 12 p.

    Research output: Contribution to journalArticle

  9. Published

    Sequence-specific solution NMR assignments of the β-barrel insertase BamA to monitor its conformational ensemble at the atomic level

    Jean-Baptiste Hartmann, Dr Michael Zahn, Irena Matečko Burmann, Stefan Bibow & Sebastian Hiller, 12 Sep 2018, In : Journal of the American Chemical Society. 140, 36, p. 11252-11260 9 p.

    Research output: Contribution to journalArticle

  10. Published

    Crystal structure of the Acinetobacter baumannii outer membrane protein Omp33

    Javier Abellón-Ruiz, Dr Michael Zahn, Arnaud Baslé & Bert Van Den Berg, 1 Sep 2018, In : Acta Crystallographica Section D Structural Biology. D74, 9, p. 852-860

    Research output: Contribution to journalArticle

  11. 2016
  12. Published

    Structural insights into outer membrane permeability of Acinetobacter baumannii

    Dr Michael Zahn, Satya prathyusha Bhamidimarri, Arnaud Baslé, Mathias Winterhalter & Bert Van den Berg, 1 Feb 2016, In : Structure. 24, 2, p. 221-231

    Research output: Contribution to journalArticle

  13. 2015
  14. Published

    Small-molecule transport by CarO, an abundant eight-stranded β-barrel outer membrane protein from Acinetobacter baumannii

    Dr Michael Zahn, Tommaso D'agostino, Elif Eren, Arnaud Baslé, Matteo Ceccarelli & Bert Van Den Berg, 1 Jul 2015, In : Journal of Molecular Biology. 427, 14, p. 2329-2339

    Research output: Contribution to journalArticle

  15. Published

    Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase

    Nadya Kurteva-Yaneva, Dr Michael Zahn, M.-Teresa Weichler, Robert Starke, Hauke Harms, Roland H. Müller, Norbert Sträter & Thore Rohwerder, 10 Apr 2015, In : Journal of Biological Chemistry. 290, 15, p. 9727-9737

    Research output: Contribution to journalArticle

  16. 2014
  17. Published

    Fluorine-containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10 A: synthesis and in vitro evaluation of inhibitory potency, selectivity, and metabolism

    Gregor Schwan, Ghadir Barbar Asskar, Norbert Höfgen, Lenka Kubicova, Uta Funke, Ute Egerland, Dr Michael Zahn, Karen Nieber, Matthias Scheunemann, Norbert Sträter & 2 others, Peter Brust & Detlef Briel, 1 Jul 2014, In : ChemMedChem. 9, 7, p. 1476-1487 12 p.

    Research output: Contribution to journalArticle

  18. Published

    Structural identification of DnaK binding sites within bovine and sheep bactenecin Bac7

    Dr Michael Zahn, Björn Kieslich, Nicole Berthold, Daniel Knappe, Ralf Hoffmann & Norbert Sträter, 1 Apr 2014, In : Protein and Peptide Letters. 21, 4, p. 407-412 6 p.

    Research output: Contribution to journalArticle

  19. 2013
  20. Published

    Structural studies on the forward and reverse binding modes of peptides to the chaperone DnaK

    Dr Michael Zahn, Nicole Berthold, Björn Kieslich, Daniel Knappe, Ralf Hoffmann & Norbert Sträter, 24 Jul 2013, In : Journal of Molecular Biology. 425, 14, p. 2463-2479 14 p.

    Research output: Contribution to journalArticle

  21. 2012
  22. Published

    Api88 Is a novel antibacterial designer peptide to treat systemic infections with multidrug-resistant Gram-negative pathogens

    Patricia Czihal, Daniel Knappe, Stefanie Fritsche, Dr Michael Zahn, Nicole Berthold, Stefania Piantavigna, Uwe Müller, Sylvia Van Dorpe, Nicole Herth, Annegret Binas & 7 others, Gabriele Köhler, Bart De Spiegeleer, Lisandra L. Martin, Oliver Nolte, Norbert Sträter, Gottfried Alber & Ralf Hoffmann, 20 Jul 2012, In : ACS Chemical Biology. 7, 7, p. 1281-1291 11 p.

    Research output: Contribution to journalArticle

  23. Published

    Crystal structure of a supercharged variant of the human enteropeptidase light chain

    Peter Simeonov, Dr Michael Zahn, Norbert Sträter & Thole Zuchner, 1 Jul 2012, In : Proteins: Structure, Function, Bioinformatics. 80, 7, p. 1907-1910 4 p.

    Research output: Contribution to journalArticle

  24. 2011
  25. Published

    Rational design of oncocin derivatives with superior protease stabilities and antibacterial activities based on the high-resolution structure of the oncocin-DnaK complex

    Daniel Knappe, Dr Michael Zahn, Ute Sauer, Guido Schiffer, Norbert Sträter & Ralf Hoffmann, 11 Apr 2011, In : ChemBioChem. 12, 6, p. 874-876 3 p.

    Research output: Contribution to journalArticle

ID: 15728738