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Dr Patricia Madureira

Visiting Senior Research Fellow

  1. 2019
  2. Early online

    Corrigendum to “IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas.” [Cancer Lett. 458C (2019) 29–38]

    K. Mihajluk, C. Simms, M. Reay, Dr Patricia Madureira, A. Howarth, P. Murray, S. Nasser, C.A. Duckworth, D.M. Pritchard, Professor Geoff Pilkington & 1 others, R. Hill, 8 Oct 2019, In : Cancer Letters.

    Research output: Contribution to journalComment/debate

  3. Published

    DIVERSet JAG compounds inhibit topoisomerase II and are effective against adult and pediatric high-grade gliomas

    Alison Howarth, Claire Simms, Nitesh Kerai, Olivia Allen, Karina Mihajluk, Dr Patricia Madureira, Giannis Sokratous, Professor Simon Cragg, Sang Y. Lee, Andy D. Morley & 4 others, Ashkan Keyoumars, Dr Paul Cox, Professor Geoff Pilkington & Richard Hill, 1 Oct 2019, In : Translational Oncology. 12, 10, p. 1375-1385

    Research output: Contribution to journalArticle

  4. Published

    IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas

    K. Mihajluk, C. Simms, M. Reay, Dr Patricia Madureira, A. Howarth, P. Murray, S. Nasser, C. A. Duckworth, D. M. Pritchard, Professor Geoff Pilkington & 1 others, R. Hill, 28 Aug 2019, In : Cancer Letters. 458, p. 29-38 10 p.

    Research output: Contribution to journalArticle

  5. Early online

    Modulating autophagy as a therapeutic strategy for the treatment of paediatric high grade glioma

    Alison Howarth, Dr Patricia Madureira, George Lockwood, Lisa C. D. Storer, Richard Grundy, Ruman Rahman, Professor Geoff Pilkington & Richard Hill, 13 May 2019, In : Brain Pathology. 19 p.

    Research output: Contribution to journalReview article

  6. Published

    Annexin A2 regulates AKT upon H2O2-dependent signaling activation in cancer cells

    Stéphanie Anais Castaldo, Tom Ajime, Gisela Serrão, Fábio Anastácio, Joana Teixeira Rosa, Carman Anthony Giacomantonio, Alison Howarth, Richard Hill & Dr Patricia Madureira, 7 Apr 2019, In : Cancers. 11, 4, 492.

    Research output: Contribution to journalArticle

  7. 2017
  8. Published

    The role of hypoxia in glioblastoma invasion

    Ana Rita Monteiro, Richard Hill, Professor Geoff Pilkington & Dr Patricia Madureira, 22 Nov 2017, In : Stem Cells. 6, 4, 24 p., 45.

    Research output: Contribution to journalLiterature review

  9. Published

    Mechanism of plasmin generation by S100A10

    Victoria A. Miller, Dr Patricia Madureira, Ain Adilliah Kamaludin, Jeffrey Komar, Vandna Sharma, Girish Sahni, Craig Thelwell, Colin Longstaff & David M. Waisman, 2 Jun 2017, In : Thrombosis and Haemostasis. 117, 6, p. 1058-1071 14 p.

    Research output: Contribution to journalArticle

  10. Early online

    TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT

    Richard Hill, Dr Patricia Madureira, Bibiana Ferreira, Inês Baptista, Susana Machado, Laura Colaço, Marta dos Santos, Ningshu Liu, Ana Dopazo, Selma Ugurel & 5 others, Angyal Adrienn, Endre Kiss-Toth, Murat Isbilen, Ali O. Gure & Wolfgang Link, 9 Mar 2017, In : Nature Communications. 8, 14687.

    Research output: Contribution to journalArticle

  11. 2016
  12. Published

    Cell surface protease activation during RAS transformation: critical role of the plasminogen receptor, S100A10

    Dr Patricia Madureira, Alamelu G. Bharadwaj, Moamen Bydoun, Katy Garant, Paul O'Connell, Patrick Lee & David M. Waisman, 24 Jun 2016, In : Oncotarget. 7, 30, p. 47720-47737 18 p.

    Research output: Contribution to journalArticle

  13. Published

    The tumorigenic roles of the cellular REDOX regulatory systems

    Stéphanie Anaís Castaldo, Joana Raquel Freitas, Nadine Vasconcelos Conchinha & Dr Patricia Madureira, 1 Jan 2016, In : Oxidative Medicine and Cellular Longevity. 2016, 17 p., 8413032.

    Research output: Contribution to journalLiterature review

  14. 2013
  15. Published

    Gemcitabine-mediated tumour regression and p53-dependent gene expression: implications for colon and pancreatic cancer therapy

    R. Hill, M. Rabb, Dr Patricia Madureira, D. Clements, S. A. Gujar, D. M. Waisman, C. A. Giacomantonio & P. W. K. Lee, 5 Sep 2013, In : Cell Death and Disease. 4, 9, e791.

    Research output: Contribution to journalArticle

  16. Published

    Identifying new targets for personalised cancer therapy

    W. Link, Dr Patricia Madureira & Richard Hill, May 2013, Encyclopedia of Life Sciences. Wiley

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  17. Published

    Annexin A2: The Importance of Being Redox Sensitive

    Dr Patricia Madureira & David M Waisman, 7 Feb 2013, In : International Journal of Molecular Sciences. 14, 2, p. 3568-3594 27 p.

    Research output: Contribution to journalArticle

  18. 2012
  19. Published

    Genotoxic agents promote the nuclear accumulation of annexin A2: role of annexin A2 in mitigating DNA damage

    Dr Patricia Madureira, Richard Hill, Patrick W. K. Lee & David M. Waisman, 30 Nov 2012, In : PLoS One. 7, 11, e50591.

    Research output: Contribution to journalArticle

  20. Published

    The biochemistry and regulation of S100A10: a multifunctional plasminogen receptor involved in oncogenesis

    Dr Patricia Madureira, Paul A O'Connell, Alexi P Surette, Victoria A Miller & David M Waisman, 2012, In : Journal of Biomedicine and Biotechnology. 2012, 21 p., 353687.

    Research output: Contribution to journalReview article

  21. 2011
  22. Published

    Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis

    Dr Patricia Madureira, Richard Hill, Victoria Ann Miller, Carman Giacomantonio, Patrick W. K. Lee & David Morton Waisman, 20 Dec 2011, In : Oncotarget. 2, 12, p. 1075-1093 19 p.

    Research output: Contribution to journalArticle

  23. Published

    DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death

    Richard Hill, Dr Patricia Madureira, David M. Waisman & Patrick W. K. Lee, 20 Dec 2011, In : Oncotarget. 2, 12, p. 1094-1108 15 p.

    Research output: Contribution to journalArticle

  24. Published

    The role of the annexin A2 heterotetramer in vascular fibrinolysis

    Dr Patricia Madureira, Alexi P Surette, Kyle D Phipps, Michael A S Taboski, Victoria A Miller & David M Waisman, 3 Nov 2011, In : Blood. 118, 18, p. 4789-4797 9 p.

    Research output: Contribution to journalReview article

  25. Published

    Regulation of fibrinolysis by S100A10 in vivo

    Alexi P Surette, Dr Patricia Madureira, Kyle D Phipps, Victoria A Miller, Per Svenningsson & David M Waisman, 15 Sep 2011, In : Blood. 118, 11, p. 3172-3181 10 p.

    Research output: Contribution to journalArticle

  26. Published

    Regulation of S100A10 by the PML-RAR-α oncoprotein

    Paul A O'Connell, Dr Patricia Madureira, Jason N Berman, Robert S Liwski & David M Waisman, 14 Apr 2011, In : Blood. 117, 15, p. 4095-4105 11 p.

    Research output: Contribution to journalArticle

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