Dr Qian An
Senior Lecturer, Senior Research Fellow
I am a molecular biologist with a major research interest in genetic abnormalities in human cancers as biomarkers for cancer diagnosis, prognosis and treatment. I gained a PhD in Molecular Oncology and completed my early post-doctoral training at Cancer Research UK and Southampton University, where my research on oxidative DNA damage led to a better clarification of the cytotoxic mechanism of the anti-cancer drug 5-FU. During that period I also established a model which may help to understand the molecular consequences of unbalanced translocations in human cancer. I joined the Neuro-oncology Research Group led by Prof. Geoff Pilkington at Portsmouth University in 2009 and I have recently become an HEFCE-funded Senior Research Fellow. Currently I am investigating mitochondrial abnormalities in the development and progression of human cancers, novel therapeutic agents across blood-brain barrier, the Gas6/Axl pathway in brain tumour chemosensitivity, and improved gene therapy of Duchenne muscular dystrophy.
For more information about my research please visit my lab page.
Mitochondrial abnormalities in the development and progression of human cancers;
Novel therapeutic agents across blood-brain barrier;
The Gas6/Axl pathway in brain tumour chemosensitivity;
Improved gene therapy of Duchenne muscular dystrophy.