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Dr Sam Robson

Senior Research Fellow (Bioinformatics)

  1. 2019
  2. Accepted for publication

    Total absence of dystrophin expression exacerbates ectopic myofibre calcification, fibrosis and alters macrophage infiltration patterns

    Young, C., Gosselin, M. R. F., Rumney, R. M. H., Oksiejuk, A., Chira, N., Bozycki, L., Matryba, P., Łukasiewicz, K., Kao, A., Dunlop, J. N. & 3 others, Dr Samuel Robson, Zabłocki, K. & Professor Darek Gorecki, 26 Sep 2019, (Accepted for publication) In : American Journal of Pathology.

    Research output: Contribution to journalArticle

  3. Published

    Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

    Samudyata, Amaral, P. P., Engström, P. G., Dr Samuel Robson, Nielsen, M. L., Kouzarides, T. & Castelo-Branco, G., 1 Aug 2019, In : Experimental Cell Research. 381, 1, p. 129-138

    Research output: Contribution to journalArticle

  4. Published

    METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation

    Pandolfini, L., Barbieri, I., Bannister, A. J., Hendrick, A., Andrews, B., Webster, N., Murat, P., Mach, P., Brandi, R., Robson, S. C. & 5 others, Migliori, V., Alendar, A., D’Onofrio, M., Balasubramanian, S. & Kouzarides, T., 20 Jun 2019, In : Molecular Cell. 74, 6, p. 1278-1290.e9

    Research output: Contribution to journalArticle

  5. Early online

    Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling

    Róg, J., Oksiejuk, A., Maxime Raymond Fernand Gosselin, Brutkowski, W., Dymkowska, D., Nowak, N., Dr Samuel Robson, Professor Darek Gorecki & Zabłocki, K., 24 Jan 2019, In : Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

    Research output: Contribution to journalArticle

  6. 2018
  7. Published

    SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

    Tzelepis, K., De Braekeleer, E., Aspris, D., Barbieri, I., Vijayabaskar, M. S., Liu, W., Gozdecka, M., Metzakopian, E., Toop, H. D., Dudek, M. & 25 others, Dr Samuel Robson, Hermida-Prado, F., Yang, Y. H., Babaei-Jadidi, R., Garyfallos, D. A., Ponstingl, H., Dias, J. M. L., Gallipoli, P., Seiler, M., Buonamici, S., Vick, B., Bannister, A. J., Rad, R., Prinjha, R. K., Marioni, J. C., Huntly, B., Batson, J., Morris, J. C., Pina, C., Bradley, A., Jeremias, I., Bates, D. O., Yusa, K., Kouzarides, T. & Vassiliou, G. S., 19 Dec 2018, In : Nature Communications. 9, 1, 5378.

    Research output: Contribution to journalArticle

  8. Published

    Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery

    Millan-Zambrano, G., Santos-Rosa, H., Puddu, F., Dr Samuel Robson, Jackson, S. P. & Kouzarides, T., 15 Nov 2018, In : Molecular Cell. 72, 4, p. 625-635.e4

    Research output: Contribution to journalArticle

  9. Published

    Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

    Larrieu, D., Viré, E., Dr Samuel Robson, Breusegem, S. Y., Kouzarides, T. & Jackson, S. P., 3 Jul 2018, In : Science Signaling. 11, 537, eaar5401.

    Research output: Contribution to journalArticle

  10. 2017
  11. Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

    Barbieri, I., Tzelepis, K., Pandolfini, L., Shi, J., Millán-zambrano, G., Robson, S. C., Aspris, D., Migliori, V., Bannister, A. J., Han, N. & 6 others, De Braekeleer, E., Ponstingl, H., Hendrick, A., Vakoc, C. R., Vassiliou, G. S. & Kouzarides, T., 7 Dec 2017, In : Nature. 552, p. 126-131 6 p.

    Research output: Contribution to journalArticle

  12. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

    Li, M. A., Amaral, P. P., Cheung, P., Bergmann, J. H., Kinoshita, M., Kalkan, T., Ralser, M., Robson, S., Meyenn, F. V., Paramor, M. & 7 others, Yang, F., Chen, C., Nichols, J., Spector, D. L., Kouzarides, T., He, L. & Smith, A., 18 Aug 2017, In : eLife. 6, e23468.

    Research output: Contribution to journalArticle

  13. RNA binding by the histone methyltransferases Set1 and Set2

    Sayou, C., Millán-Zambrano, G., Santos-Rosa, H., Petfalski, E., Dr Samuel Robson, Houseley, J., Kouzarides, T. & Tollervey, D., Jul 2017, In : Molecular and Cellular Biology. 37, 14, e00165-17.

    Research output: Contribution to journalArticle

  14. 2016
  15. A chemical probe for the ATAD2 bromodomain

    Bamborough, P., Chung, C., Demont, E. H., Furze, R. C., Bannister, A. J., Che, K. H., Diallo, H., Douault, C., Grandi, P., Kouzarides, T. & 8 others, Michon, A-M., Mitchell, D. J., Prinjha, R. K., Rau, C., Dr Samuel Robson, Sheppard, R. J., Upton, R. & Watson, R. J., 12 Sep 2016, In : Angewandte Chemie International Edition. 55, 38, p. 11382-11386 5 p.

    Research output: Contribution to journalArticle

  16. Published

    Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition

    Theodoulou, N. H., Bamborough, P., Bannister, A. J., Becher, I., Bit, R. A., Che, K. H., Chung, C., Dittmann, A., Drewes, G., Drewry, D. H. & 11 others, Gordon, L., Grandi, P., Leveridge, M., Lindon, M., Michon, A-M., Molnar, J., Dr Samuel Robson, Tomkinson, N. C. O., Kouzarides, T., Prinjha, R. K. & Humphreys, P. G., 25 Feb 2016, In : Journal of Medicinal Chemistry. 59, 4, p. 1425-1439

    Research output: Contribution to journalArticle

  17. 2015
  18. Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy

    Picaud, S., Fedorov, O., Thanasopoulou, A., Leonards, K., Jones, K., Meier, J., Olzscha, H., Monteiro, O., Martin, S., Philpott, M. & 27 others, Tumber, A., Filippakopoulos, P., Yapp, C., Wells, C., Che, K. H., Bannister, A. J., Dr Samuel Robson, Kumar, U., Parr, N., Lee, H. K., Lugo, D., Jeffrey, P., Taylor, R. S., Vecellio, M. L., Bountra, C., Brennan, P. E., O'Mahony, A., Velichko, S., Muller, S., Hay, D., Daniels, D. L., Urh, M., La Thangue, N. B., Kouzarides, T., Prinjha, R. K., Schwaller, J. & Knapp, S., 1 Dec 2015, In : Cancer Research. 75, 23, p. 5106-5119 14 p.

    Research output: Contribution to journalArticle

  19. 2014
  20. Published

    The breast cancer oncogene EMSY Represses transcription of antimetastatic microRNA miR-31

    Viré, E., Curtis, C., Davalos, V., Git, A., Robson, S., Villanueva, A., Vidal, A., Barbieri, I., Aparicio, S., Esteller, M. & 2 others, Caldas, C. & Kouzarides, T., 1 Mar 2014, In : Molecular Cell. 53, 5, p. 806-818 13 p.

    Research output: Contribution to journalArticle

  21. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

    Dawson, M. A., Gudgin, E. J., Horton, S. J., Giotopoulos, G., Meduri, E., Robson, S., Cannizzaro, E., Osaki, H., Wiese, M., Putwain, S. & 13 others, Fong, C. Y., Grove, C., Craig, J., Dittmann, A., Lugo, D., Jeffrey, P., Drewes, G., Lee, H. K., Bullinger, L., Prinjha, R. K., Kouzarides, T., Vassiliou, G. S. & Huntly, B. J. P., 1 Feb 2014, In : Leukaemia. 28, 2, p. 311-320 10 p.

    Research output: Contribution to journalArticle

  22. Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Tessarz, P., Santos-Rosa, H., Dr Samuel Robson, Sylvestersen, K. B., Nelson, C. J., Nielsen, M. L. & Kouzarides, T., 23 Jan 2014, In : Nature. 505, 7484, p. 564-568 5 p.

    Research output: Contribution to journalArticle

  23. Published

    BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms

    Wyspiańska, B. S., Bannister, A. J., Barbieri, I., Nangalia, J., Godfrey, A., Calero-nieto, F. J., Robson, S., Rioja, I., Li, J., Wiese, M. & 7 others, Cannizzaro, E., Dawson, M. A., Huntly, B. J. P., Prinjha, R. K., Green, A. R., Gottgens, B. & Kouzarides, T., 1 Jan 2014, In : Leukaemia. 28, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  24. 2013
  25. The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells

    Castelo-Branco, G., Amaral, P. P., Engström, P. G., Dr Samuel Robson, Marques, S. C., Bertone, P. & Kouzarides, T., 17 Sep 2013, In : Genome Biology. 14, 9, R98.

    Research output: Contribution to journalArticle

  26. 2012
  27. Human RNA methyltransferase BCDIN3D regulates microRNA processing

    Xhemalce, B., Dr Samuel Robson & Kouzarides, T., 11 Oct 2012, In : Cell. 151, 2, p. 278-288 11 p.

    Research output: Contribution to journalArticle

  28. Three distinct patterns of histone H3Y41 phosphorylation mark active genes

    Dawson, MA., Foster, SD., Bannister, AJ., Robson, SC., Hannah, R., Wang, X., Xhemalce, B., Wood, AD., Green, AR., Göttgens, B. & 1 others, Kouzarides, T., 20 Sep 2012, In : Cell Reports. 2, 3, p. 470-477 8 p.

    Research output: Contribution to journalArticle

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ID: 7024041