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Dr Sam Robson

Senior Research Fellow (Bioinformatics)

  1. 2020
  2. Early online
  3. Early online

    Subtle effects of radiation on embryo development of the 3-spined stickleback

    Dr Adelaide Lerebours, Dr Samuel Robson, Dr Colin Sharpe & Professor Jim Smith, 27 Jan 2020, In : Chemosphere. 248, 126005.

    Research output: Contribution to journalArticle

  4. Published

    Total absence of dystrophin expression exacerbates ectopic myofiber calcification and fibrosis and alters macrophage infiltration patterns

    Young, C., Gosselin, M. R. F., Rumney, R. M. H., Oksiejuk, A., Chira, N., Bozycki, L., Matryba, P., Łukasiewicz, K., Kao, A., Dunlop, J. N. & 3 others, Dr Samuel Robson, Zabłocki, K. & Professor Darek Gorecki, 1 Jan 2020, In : American Journal of Pathology. 190, 1, p. 190-205 16 p.

    Research output: Contribution to journalArticle

  5. 2019
  6. Published

    Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

    Samudyata, Amaral, P. P., Engström, P. G., Dr Samuel Robson, Nielsen, M. L., Kouzarides, T. & Castelo-Branco, G., 1 Aug 2019, In : Experimental Cell Research. 381, 1, p. 129-138

    Research output: Contribution to journalArticle

  7. Published

    METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation

    Pandolfini, L., Barbieri, I., Bannister, A. J., Hendrick, A., Andrews, B., Webster, N., Murat, P., Mach, P., Brandi, R., Robson, S. C. & 5 others, Migliori, V., Alendar, A., D’Onofrio, M., Balasubramanian, S. & Kouzarides, T., 20 Jun 2019, In : Molecular Cell. 74, 6, p. 1278-1290.e9

    Research output: Contribution to journalArticle

  8. Early online

    Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling

    Róg, J., Oksiejuk, A., Maxime Raymond Fernand Gosselin, Brutkowski, W., Dymkowska, D., Nowak, N., Dr Samuel Robson, Professor Darek Gorecki & Zabłocki, K., 24 Jan 2019, In : Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

    Research output: Contribution to journalArticle

  9. 2018
  10. Published

    SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4

    Tzelepis, K., De Braekeleer, E., Aspris, D., Barbieri, I., Vijayabaskar, M. S., Liu, W., Gozdecka, M., Metzakopian, E., Toop, H. D., Dudek, M. & 25 others, Dr Samuel Robson, Hermida-Prado, F., Yang, Y. H., Babaei-Jadidi, R., Garyfallos, D. A., Ponstingl, H., Dias, J. M. L., Gallipoli, P., Seiler, M., Buonamici, S., Vick, B., Bannister, A. J., Rad, R., Prinjha, R. K., Marioni, J. C., Huntly, B., Batson, J., Morris, J. C., Pina, C., Bradley, A., Jeremias, I., Bates, D. O., Yusa, K., Kouzarides, T. & Vassiliou, G. S., 19 Dec 2018, In : Nature Communications. 9, 1, 5378.

    Research output: Contribution to journalArticle

  11. Published

    Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery

    Millan-Zambrano, G., Santos-Rosa, H., Puddu, F., Dr Samuel Robson, Jackson, S. P. & Kouzarides, T., 15 Nov 2018, In : Molecular Cell. 72, 4, p. 625-635.e4

    Research output: Contribution to journalArticle

  12. Published

    Inhibition of the acetyltransferase NAT10 normalizes progeric and aging cells by rebalancing the Transportin-1 nuclear import pathway

    Larrieu, D., Viré, E., Dr Samuel Robson, Breusegem, S. Y., Kouzarides, T. & Jackson, S. P., 3 Jul 2018, In : Science Signaling. 11, 537, eaar5401.

    Research output: Contribution to journalArticle

  13. 2017
  14. Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

    Barbieri, I., Tzelepis, K., Pandolfini, L., Shi, J., Millán-zambrano, G., Robson, S. C., Aspris, D., Migliori, V., Bannister, A. J., Han, N. & 6 others, De Braekeleer, E., Ponstingl, H., Hendrick, A., Vakoc, C. R., Vassiliou, G. S. & Kouzarides, T., 7 Dec 2017, In : Nature. 552, p. 126-131 6 p.

    Research output: Contribution to journalArticle

  15. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

    Li, M. A., Amaral, P. P., Cheung, P., Bergmann, J. H., Kinoshita, M., Kalkan, T., Ralser, M., Robson, S., Meyenn, F. V., Paramor, M. & 7 others, Yang, F., Chen, C., Nichols, J., Spector, D. L., Kouzarides, T., He, L. & Smith, A., 18 Aug 2017, In : eLife. 6, e23468.

    Research output: Contribution to journalArticle

  16. RNA binding by the histone methyltransferases Set1 and Set2

    Sayou, C., Millán-Zambrano, G., Santos-Rosa, H., Petfalski, E., Dr Samuel Robson, Houseley, J., Kouzarides, T. & Tollervey, D., Jul 2017, In : Molecular and Cellular Biology. 37, 14, e00165-17.

    Research output: Contribution to journalArticle

  17. 2016
  18. A chemical probe for the ATAD2 bromodomain

    Bamborough, P., Chung, C., Demont, E. H., Furze, R. C., Bannister, A. J., Che, K. H., Diallo, H., Douault, C., Grandi, P., Kouzarides, T. & 8 others, Michon, A-M., Mitchell, D. J., Prinjha, R. K., Rau, C., Dr Samuel Robson, Sheppard, R. J., Upton, R. & Watson, R. J., 12 Sep 2016, In : Angewandte Chemie International Edition. 55, 38, p. 11382-11386 5 p.

    Research output: Contribution to journalArticle

  19. Published

    Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition

    Theodoulou, N. H., Bamborough, P., Bannister, A. J., Becher, I., Bit, R. A., Che, K. H., Chung, C., Dittmann, A., Drewes, G., Drewry, D. H. & 11 others, Gordon, L., Grandi, P., Leveridge, M., Lindon, M., Michon, A-M., Molnar, J., Dr Samuel Robson, Tomkinson, N. C. O., Kouzarides, T., Prinjha, R. K. & Humphreys, P. G., 25 Feb 2016, In : Journal of Medicinal Chemistry. 59, 4, p. 1425-1439

    Research output: Contribution to journalArticle

  20. 2015
  21. Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy

    Picaud, S., Fedorov, O., Thanasopoulou, A., Leonards, K., Jones, K., Meier, J., Olzscha, H., Monteiro, O., Martin, S., Philpott, M. & 27 others, Tumber, A., Filippakopoulos, P., Yapp, C., Wells, C., Che, K. H., Bannister, A. J., Dr Samuel Robson, Kumar, U., Parr, N., Lee, H. K., Lugo, D., Jeffrey, P., Taylor, R. S., Vecellio, M. L., Bountra, C., Brennan, P. E., O'Mahony, A., Velichko, S., Muller, S., Hay, D., Daniels, D. L., Urh, M., La Thangue, N. B., Kouzarides, T., Prinjha, R. K., Schwaller, J. & Knapp, S., 1 Dec 2015, In : Cancer Research. 75, 23, p. 5106-5119 14 p.

    Research output: Contribution to journalArticle

  22. 2014
  23. Published

    The breast cancer oncogene EMSY Represses transcription of antimetastatic microRNA miR-31

    Viré, E., Curtis, C., Davalos, V., Git, A., Robson, S., Villanueva, A., Vidal, A., Barbieri, I., Aparicio, S., Esteller, M. & 2 others, Caldas, C. & Kouzarides, T., 1 Mar 2014, In : Molecular Cell. 53, 5, p. 806-818 13 p.

    Research output: Contribution to journalArticle

  24. Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia

    Dawson, M. A., Gudgin, E. J., Horton, S. J., Giotopoulos, G., Meduri, E., Robson, S., Cannizzaro, E., Osaki, H., Wiese, M., Putwain, S. & 13 others, Fong, C. Y., Grove, C., Craig, J., Dittmann, A., Lugo, D., Jeffrey, P., Drewes, G., Lee, H. K., Bullinger, L., Prinjha, R. K., Kouzarides, T., Vassiliou, G. S. & Huntly, B. J. P., 1 Feb 2014, In : Leukaemia. 28, 2, p. 311-320 10 p.

    Research output: Contribution to journalArticle

  25. Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Tessarz, P., Santos-Rosa, H., Dr Samuel Robson, Sylvestersen, K. B., Nelson, C. J., Nielsen, M. L. & Kouzarides, T., 23 Jan 2014, In : Nature. 505, 7484, p. 564-568 5 p.

    Research output: Contribution to journalArticle

  26. Published

    BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms

    Wyspiańska, B. S., Bannister, A. J., Barbieri, I., Nangalia, J., Godfrey, A., Calero-nieto, F. J., Robson, S., Rioja, I., Li, J., Wiese, M. & 7 others, Cannizzaro, E., Dawson, M. A., Huntly, B. J. P., Prinjha, R. K., Green, A. R., Gottgens, B. & Kouzarides, T., 1 Jan 2014, In : Leukaemia. 28, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticle

  27. 2013
  28. The non-coding snRNA 7SK controls transcriptional termination, poising, and bidirectionality in embryonic stem cells

    Castelo-Branco, G., Amaral, P. P., Engström, P. G., Dr Samuel Robson, Marques, S. C., Bertone, P. & Kouzarides, T., 17 Sep 2013, In : Genome Biology. 14, 9, R98.

    Research output: Contribution to journalArticle

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