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Dr Sam Robson

Senior Research Fellow (Bioinformatics)

  1. A chemical probe for the ATAD2 bromodomain

    Paul Bamborough, Chun-wa Chung, Emmanuel H. Demont, Rebecca C. Furze, Andrew J. Bannister, Ka Hing Che, Hawa Diallo, Clement Douault, Paola Grandi, Tony Kouzarides & 8 others, Anne-Marie Michon, Darren J. Mitchell, Rab K. Prinjha, Christina Rau, Dr Samuel Robson, Robert J. Sheppard, Richard Upton & Robert J. Watson, 12 Sep 2016, In: Angewandte Chemie International Edition. 55, 38, p. 11382-11386 5 p.

    Research output: Contribution to journalArticlepeer-review

  2. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

    Meng Amy Li, Paulo P. Amaral, Priscilla Cheung, Jan H. Bergmann, Masaki Kinoshita, Tüzer Kalkan, Meryem Ralser, Dr Samuel Robson, Ferdinand von Meyenn, Maike Paramor & 7 others, Fengtang Yang, Caifu Chen, Jennifer Nichols, David L. Spector, Tony Kouzarides, Lin He & Austin Smith, 18 Aug 2017, In: eLife. 6, e23468.

    Research output: Contribution to journalArticlepeer-review

  3. Published
  4. Published

    An integrated national scale SARS-CoV-2 genomic surveillance network

    The COVID-19 Genomics UK (COG-UK) Consortium, Dr Samuel Robson, Dr Garry Scarlett, Dr Yann Xavier Claude Bourgeois & Miss Angela Helen Beckett, 1 Jul 2020, In: The Lancet Microbe. 1, p. e99-e100

    Research output: Contribution to journalComment/debatepeer-review

  5. Published

    BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms

    B. S. Wyspiańska, Andrew J. Bannister, Isaia Barbieri, J. Nangalia, A. Godfrey, F. J. Calero-nieto, Dr Samuel Robson, I. Rioja, J. Li, M. Wiese & 7 others, E. Cannizzaro, M. A. Dawson, B. J. P. Huntly, Rab K. Prinjha, A. R. Green, B. Gottgens & Tony Kouzarides, 1 Jan 2014, In: Leukaemia. 28, 1, p. 88-97 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published
  7. Published

    Complete transcriptome assembly and annotation of a critically important amphipod species in freshwater ecotoxicological risk assessment: gammarus fossarum

    Domenico Roberto Caputo, Dr Samuel Robson, Inge Werner & Professor Alex Ford, 1 Apr 2020, In: Environment International. 137, 10 p., 105319.

    Research output: Contribution to journalArticlepeer-review

  8. Published
  9. Deciphering c-MYC-regulated genes in two distinct tissues

    Dr Samuel Robson, Lesley Ward, Helen Brown, Heather Turner, Ewan Hunter, Stella Pelengaris & Michael Khan, 1 Dec 2011, In: BMC Genomics. 12, 1, 476.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition

    Natalie H. Theodoulou, Paul Bamborough, Andrew J. Bannister, Isabelle Becher, Rino A. Bit, Ka Hing Che, Chun-wa Chung, Antje Dittmann, Gerard Drewes, David H. Drewry & 11 others, Laurie Gordon, Paola Grandi, Melanie Leveridge, Matthew Lindon, Anne-Marie Michon, Judit Molnar, Dr Samuel Robson, Nicholas C. O. Tomkinson, Tony Kouzarides, Rab K. Prinjha & Philip G. Humphreys, 25 Feb 2016, In: Journal of Medicinal Chemistry. 59, 4, p. 1425-1439

    Research output: Contribution to journalArticlepeer-review

  11. Early online

    Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling

    Justyna Róg, Aleksandra Oksiejuk, Maxime Raymond Fernand Gosselin, Wojciech Brutkowski, Dorota Dymkowska, Natalia Nowak, Dr Samuel Robson, Professor Darek Gorecki & Krzysztof Zabłocki, 24 Jan 2019, (Early online) In: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

    Research output: Contribution to journalArticlepeer-review

  12. Published
  13. Published

    Functionality and composition of marine biofilms on antifouling coatings.

    Maria Papadatou, Dr Samuel Robson, Professor Joy Watts, Sergey Dobretsov & Dr Maria Salta, Oct 2020.

    Research output: Contribution to conferencePosterpeer-review

  14. Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy

    S. Picaud, O. Fedorov, A. Thanasopoulou, K. Leonards, K. Jones, J. Meier, H. Olzscha, O. Monteiro, S. Martin, M. Philpott & 27 others, A. Tumber, P. Filippakopoulos, C. Yapp, C. Wells, Ka Hing Che, Andrew J. Bannister, Dr Samuel Robson, U. Kumar, N. Parr, H. K. Lee, D. Lugo, P. Jeffrey, Rod S. Taylor, M. L. Vecellio, C. Bountra, P. E. Brennan, A. O'Mahony, S. Velichko, S. Muller, D. Hay, D. L. Daniels, M. Urh, N. B. La Thangue, Tony Kouzarides, Rab K. Prinjha, J. Schwaller & S. Knapp, 1 Dec 2015, In: Cancer Research. 75, 23, p. 5106-5119 14 p.

    Research output: Contribution to journalArticlepeer-review

  15. Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock, Matthew E. Hurles, Niall Cardin, Richard D. Pearson, Vincent Plagnol, Dr Samuel Robson, Damjan Vukcevic, Chris Barnes, Donald F. Conrad, Eleni Giannoulatou & 207 others, Chris Holmes, Jonathan L. Marchini, Kathy Stirrups, Martin D. Tobin, Louise V. Wain, Chris Yau, Jan Aerts, Tariq Ahmad, T. Daniel Andrews, Hazel Arbury, Anthony Attwood, Adam Auton, Stephen G. Ball, Anthony J. Balmforth, Jeffrey C. Barrett, Inês Barroso, Anne Barton, Amanda J. Bennett, Sanjeev Bhaskar, Katarzyna Blaszczyk, John Bowes, Oliver J. Brand, Peter S. Braund, Francesca Bredin, Gerome Breen, Morris J. Brown, Ian N. Bruce, Jaswinder Bull, Oliver S. Burren, John Burton, Jake Byrnes, Sian Caesar, Chris M. Clee, Alison J. Coffey, John M. C. Connell, Jason D. Cooper, Anna F. Dominiczak, Kate Downes, Hazel E. Drummond, Darshna Dudakia, Andrew Dunham, Bernadette Ebbs, Diana Eccles, Sarah Edkins, Cathryn Edwards, Anna Elliot, Paul Emery, David M. Evans, Gareth Evans, Steve Eyre, Anne Farmer, I. Nicol Ferrier, Lars Feuk, Tomas Fitzgerald, Edward Flynn, Alistair Forbes, Liz Forty, Jayne A. Franklyn, Rachel M. Freathy, Polly Gibbs, Paul Gilbert, Omer Gokumen, Katherine Gordon-smith, Emma Gray, Elaine Green, Chris J. Groves, Detelina Grozeva, Rhian Gwilliam, Anita Hall, Naomi Hammond, Matt Hardy, Pile Harrison, Neelam Hassanali, Husam Hebaishi, Sarah Hines, Anne Hinks, Graham A Hitman, Lynne Hocking, Eleanor Howard, Philip Howard, Joanna M. M. Howson, Debbie Hughes, Sarah Hunt, John D. Isaacs, Mahim Jain, Derek P. Jewell, Toby Johnson, Jennifer D. Jolley, Ian R. Jones, Lisa A. Jones, George Kirov, Cordelia F. Langford, Hana Lango-allen, G. Mark Lathrop, James Lee, Kate L. Lee, Charlie Lees, Kevin Lewis, Cecilia M. Lindgren, Meeta Maisuria-armer, Julian Maller, John Mansfield, Paul Martin, Dunecan C. O. Massey, Wendy L. Mcardle, Peter Mcguffin, Kirsten E. Mclay, Alex Mentzer, Michael L. Mimmack, Ann E. Morgan, Andrew P. Morris, Craig Mowat, Simon Myers, William Newman, Elaine R. Nimmo, Michael C. O’donovan, Abiodun Onipinla, Ifejinelo Onyiah, Nigel R. Ovington, Michael J. Owen, Kimmo Palin, Kirstie Parnell, David Pernet, John R. B. Perry, Anne Phillips, Dalila Pinto, Natalie J. Prescott, Inga Prokopenko, Michael A. Quail, Suzanne Rafelt, Nigel W. Rayner, Richard Redon, David M. Reid, Anthony Renwick, Susan M. Ring, Neil Robertson, Ellie Russell, David St Clair, Jennifer G. Sambrook, Jeremy D. Sanderson, Helen Schuilenburg, Carol E. Scott, Richard Scott, Sheila Seal, Sue Shaw-hawkins, Beverley M. Shields, Matthew J. Simmonds, Debbie J. Smyth, Elilan Somaskantharajah, Katarina Spanova, Sophia Steer, Jonathan Stephens, Helen E. Stevens, Millicent A. Stone, Zhan Su, Deborah P. M. Symmons, John R. Thompson, Wendy Thomson, Mary E. Travers, Clare Turnbull, Armand Valsesia, Mark Walker, Neil M. Walker, Chris Wallace, Margaret Warren-perry, Nicholas A. Watkins, John Webster, Michael N. Weedon, Anthony G. Wilson, Matthew Woodburn, B. Paul Wordsworth, Allan H. Young, Eleftheria Zeggini, Nigel P. Carter, Timothy M. Frayling, Charles Lee, Gil Mcvean, Patricia B. Munroe, Aarno Palotie, Stephen J. Sawcer, Stephen W. Scherer, David P. Strachan, Chris Tyler-smith, Matthew A. Brown, Paul R. Burton, Mark J. Caulfield, Alastair Compston, Martin Farrall, Stephen C. L. Gough, Alistair S. Hall, Andrew T. Hattersley, Adrian V. S. Hill, Christopher G. Mathew, Marcus Pembrey, Jack Satsangi, Michael R. Stratton, Jane Worthington, Panos Deloukas, Audrey Duncanson, Dominic P. Kwiatkowski, Mark I. Mccarthy, Willem H. Ouwehand, Miles Parkes, Nazneen Rahman, John A. Todd, Nilesh J. Samani & Peter Donnelly, 1 Apr 2010, In: Nature. 464, 7289, p. 713-720 8 p.

    Research output: Contribution to journalArticlepeer-review

  16. Published
  17. Published

    Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

    The WHO European Region sequencing laboratories and GISAID EpiCoV group, Dr Samuel Robson, Dr Garry Scarlett, Dr Katie Frances Loveson & Miss Angela Helen Beckett, 13 Aug 2020, In: Eurosurveillance. 25, 32, 8 p.

    Research output: Contribution to journalArticlepeer-review

  18. Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Peter Tessarz, Helena Santos-Rosa, Dr Samuel Robson, Kathrine B. Sylvestersen, Christopher J. Nelson, Michael L. Nielsen & Tony Kouzarides, 23 Jan 2014, In: Nature. 505, 7484, p. 564-568 5 p.

    Research output: Contribution to journalArticlepeer-review

  19. Human RNA methyltransferase BCDIN3D regulates microRNA processing

    Blerta Xhemalce, Dr Samuel Robson & Tony Kouzarides, 11 Oct 2012, In: Cell. 151, 2, p. 278-288 11 p.

    Research output: Contribution to journalArticlepeer-review

  20. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

    Mark A. Dawson, Rab K. Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-in Chan, Dr Samuel Robson, Chun-wa Chung, Carsten Hopf, Mikhail M. Savitski & 17 others, Carola Huthmacher, Emma Gudgin, Dave Lugo, Soren Beinke, Trevor D. Chapman, Emma J. Roberts, Peter E. Soden, Kurt R. Auger, Olivier Mirguet, Konstanze Doehner, Ruud Delwel, Alan K. Burnett, Phillip Jeffrey, Gerard Drewes, Kevin Lee, Brian J. P. Huntly & Tony Kouzarides, 2 Oct 2011, (Early online) In: Nature. 478, 7370, p. 529-533 5 p.

    Research output: Contribution to journalLetterpeer-review

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