A comparison of augmentation techniques for reconstruction of the extensor mechanism following proximal tibial replacement in an experimental animal model
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A comparison of augmentation techniques for reconstruction of the extensor mechanism following proximal tibial replacement in an experimental animal model. / Pendegrass, C. J.; Sundar, S; Oddy, M J; Cannon, S R; Briggs, T; Blunn, G W.
In: Journal of Bone and Joint Surgery - British Volume, Vol. 90, No. 4, 04.2008, p. 535-41.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A comparison of augmentation techniques for reconstruction of the extensor mechanism following proximal tibial replacement in an experimental animal model
AU - Pendegrass, C. J.
AU - Sundar, S
AU - Oddy, M J
AU - Cannon, S R
AU - Briggs, T
AU - Blunn, G W
PY - 2008/4
Y1 - 2008/4
N2 - We used an in vivo model to assess the use of an autogenous cancellous bone block and marrow graft for augmenting tendon reattachment to metallic implants. We hypothesised that augmentation of the tendon-implant interface with a bone block would enable retention of the graft on the implant surface, enhance biological integration, and result in more consistent functional outcomes compared with previously reported morcellised graft augmentation techniques. A significant improvement in functional weight-bearing was observed between six and 12 weeks. The significant increase in ground reaction force through the operated limb between six and 12 weeks was greater than that reported previously with morcellised graft augmented reconstructions. Histological appearance and collagen fibre orientation with bone block augmentation more closely resembled that of an intact enthesis compared with the morcellised grafting technique. Bone block augmentation of tendon-implant interfaces results in more reliable functional and histological outcomes, with a return to pre-operative levels of weight-bearing by 24 weeks.
AB - We used an in vivo model to assess the use of an autogenous cancellous bone block and marrow graft for augmenting tendon reattachment to metallic implants. We hypothesised that augmentation of the tendon-implant interface with a bone block would enable retention of the graft on the implant surface, enhance biological integration, and result in more consistent functional outcomes compared with previously reported morcellised graft augmentation techniques. A significant improvement in functional weight-bearing was observed between six and 12 weeks. The significant increase in ground reaction force through the operated limb between six and 12 weeks was greater than that reported previously with morcellised graft augmented reconstructions. Histological appearance and collagen fibre orientation with bone block augmentation more closely resembled that of an intact enthesis compared with the morcellised grafting technique. Bone block augmentation of tendon-implant interfaces results in more reliable functional and histological outcomes, with a return to pre-operative levels of weight-bearing by 24 weeks.
KW - Animals
KW - Bone Transplantation
KW - Female
KW - Gait
KW - Models, Animal
KW - Range of Motion, Articular
KW - Reconstructive Surgical Procedures
KW - Sheep
KW - Tendons
KW - Tibia
KW - Weight-Bearing
KW - Comparative Study
KW - Journal Article
U2 - 10.1302/0301-620X.90B4.20345
DO - 10.1302/0301-620X.90B4.20345
M3 - Article
C2 - 18378935
VL - 90
SP - 535
EP - 541
JO - Journal of Bone and Joint Surgery - British Volume
JF - Journal of Bone and Joint Surgery - British Volume
SN - 0301-620X
IS - 4
ER -
ID: 8581599