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A musical instrument using in vitro neural networks

Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • Eduardo R. Miranda
  • Slawomir J. Nasuto
  • Anna R. Troisi
  • Julia Downes
  • Antonino Chiaramonte
  • Matthew Spencer
  • Mark Hammond
  • Dimitris Xydas
  • Ben Whalley
  • Professor Victor Becerra
  • Kevin Warwick
This paper presents a musical instrument, which uses in vitro neuronal networks to synthesise sounds. Cultures of dissociated neurons are grown on a dish with an embedded rectangular array of electrodes (MEA). Isolated neurons reconnect with one another via an extensive network of synaptically connected projections to form a dense monolayer of neurons. Cultures are provided with stimulation, which influences their activity, and can modify the culture’s state. The core of the sound synthesis engine of our musical instrument is a monophonic additive synthesizer using sinusoidal oscillators. We devised a method to generate frequencies, phase and amplitude values for the oscillators from the electrical activity of the neurons.
Original languageEnglish
Title of host publicationProceedings of the International Computer Music Conference 2011, University of Huddersfield, UK, 31 July - 5 August
Place of PublicationMichigan
PublisherInternational Computer Music Association
Publication statusPublished - 2011


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