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Anisotropic time-dependant behaviour of the aortic valve

Research output: Contribution to journalArticlepeer-review

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Anisotropic time-dependant behaviour of the aortic valve. / Anssari-Benam, Afshin; Bader , Dan L.; Screen, Hazel R. C.

In: Journal of the Mechanical Behavior of Biomedical Materials, Vol. 4, No. 8, 2011, p. 1603-1610.

Research output: Contribution to journalArticlepeer-review

Harvard

Anssari-Benam, A, Bader , DL & Screen, HRC 2011, 'Anisotropic time-dependant behaviour of the aortic valve', Journal of the Mechanical Behavior of Biomedical Materials, vol. 4, no. 8, pp. 1603-1610. https://doi.org/10.1016/j.jmbbm.2011.02.010

APA

Anssari-Benam, A., Bader , D. L., & Screen, H. R. C. (2011). Anisotropic time-dependant behaviour of the aortic valve. Journal of the Mechanical Behavior of Biomedical Materials, 4(8), 1603-1610. https://doi.org/10.1016/j.jmbbm.2011.02.010

Vancouver

Anssari-Benam A, Bader DL, Screen HRC. Anisotropic time-dependant behaviour of the aortic valve. Journal of the Mechanical Behavior of Biomedical Materials. 2011;4(8):1603-1610. https://doi.org/10.1016/j.jmbbm.2011.02.010

Author

Anssari-Benam, Afshin ; Bader , Dan L. ; Screen, Hazel R. C. / Anisotropic time-dependant behaviour of the aortic valve. In: Journal of the Mechanical Behavior of Biomedical Materials. 2011 ; Vol. 4, No. 8. pp. 1603-1610.

Bibtex

@article{a79b97e564c14f9086bd1b219a8fd32d,
title = "Anisotropic time-dependant behaviour of the aortic valve",
abstract = "The complex tri-layered structure of the aortic valve (AV) results in anisotropic quasi–static mechanical behaviour. However, its influence on AV viscoelasticity remains poorly understood. Viscoelasticity may strongly influence AV dynamic mechanical behaviour, making it essential to characterise the time-dependent response for designing successful substitutes. This study attempts to characterise the time-dependent behaviour of the AV at different strain and load increments, and to gain insight into the contribution of the microstructure to this behaviour. Uniaxial incremental stress-relaxation and creep experiments were undertaken, and the experimental data analysed with a generalised Maxwell model, to determine the characteristic time-dependent parameters. Results showed that the time dependent response of the tissue differed with the loading direction, and also with the level of applied load or strain, in both stress-relaxation and creep phenomena. Both phenomena were consistently more pronounced in the radial loading direction. Fitting of the Maxwell model highlighted that the time dependent modes required to model the data also varied in different increments, and additionally with the loading direction. These results suggest that different micro-structural mechanisms may be activated in stress-relaxation and creep, determined by the microstructural organisation of the valve matrix in each loading direction, at each strain or load increment.",
author = "Afshin Anssari-Benam and Bader, {Dan L.} and Screen, {Hazel R. C.}",
year = "2011",
doi = "10.1016/j.jmbbm.2011.02.010",
language = "English",
volume = "4",
pages = "1603--1610",
journal = "Journal of the Mechanical Behavior of Biomedical Materials",
issn = "1751-6161",
publisher = "Elsevier BV",
number = "8",

}

RIS

TY - JOUR

T1 - Anisotropic time-dependant behaviour of the aortic valve

AU - Anssari-Benam, Afshin

AU - Bader , Dan L.

AU - Screen, Hazel R. C.

PY - 2011

Y1 - 2011

N2 - The complex tri-layered structure of the aortic valve (AV) results in anisotropic quasi–static mechanical behaviour. However, its influence on AV viscoelasticity remains poorly understood. Viscoelasticity may strongly influence AV dynamic mechanical behaviour, making it essential to characterise the time-dependent response for designing successful substitutes. This study attempts to characterise the time-dependent behaviour of the AV at different strain and load increments, and to gain insight into the contribution of the microstructure to this behaviour. Uniaxial incremental stress-relaxation and creep experiments were undertaken, and the experimental data analysed with a generalised Maxwell model, to determine the characteristic time-dependent parameters. Results showed that the time dependent response of the tissue differed with the loading direction, and also with the level of applied load or strain, in both stress-relaxation and creep phenomena. Both phenomena were consistently more pronounced in the radial loading direction. Fitting of the Maxwell model highlighted that the time dependent modes required to model the data also varied in different increments, and additionally with the loading direction. These results suggest that different micro-structural mechanisms may be activated in stress-relaxation and creep, determined by the microstructural organisation of the valve matrix in each loading direction, at each strain or load increment.

AB - The complex tri-layered structure of the aortic valve (AV) results in anisotropic quasi–static mechanical behaviour. However, its influence on AV viscoelasticity remains poorly understood. Viscoelasticity may strongly influence AV dynamic mechanical behaviour, making it essential to characterise the time-dependent response for designing successful substitutes. This study attempts to characterise the time-dependent behaviour of the AV at different strain and load increments, and to gain insight into the contribution of the microstructure to this behaviour. Uniaxial incremental stress-relaxation and creep experiments were undertaken, and the experimental data analysed with a generalised Maxwell model, to determine the characteristic time-dependent parameters. Results showed that the time dependent response of the tissue differed with the loading direction, and also with the level of applied load or strain, in both stress-relaxation and creep phenomena. Both phenomena were consistently more pronounced in the radial loading direction. Fitting of the Maxwell model highlighted that the time dependent modes required to model the data also varied in different increments, and additionally with the loading direction. These results suggest that different micro-structural mechanisms may be activated in stress-relaxation and creep, determined by the microstructural organisation of the valve matrix in each loading direction, at each strain or load increment.

U2 - 10.1016/j.jmbbm.2011.02.010

DO - 10.1016/j.jmbbm.2011.02.010

M3 - Article

VL - 4

SP - 1603

EP - 1610

JO - Journal of the Mechanical Behavior of Biomedical Materials

JF - Journal of the Mechanical Behavior of Biomedical Materials

SN - 1751-6161

IS - 8

ER -

ID: 917140