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Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group

Research output: Contribution to journalArticlepeer-review

Standard

Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group. / Newsom, Richard; Amara, Adam; Hicks, Alexander; Quint, Matthew; Pattison, Chris; Bzdek, Bryan R.; Burridge, James; Krawczyk, Coleman; Dinsmore, James; Conway., Joy.

In: Journal of Hospital Infection, Vol. 110, 01.04.2021, p. 194-200.

Research output: Contribution to journalArticlepeer-review

Harvard

Newsom, R, Amara, A, Hicks, A, Quint, M, Pattison, C, Bzdek, BR, Burridge, J, Krawczyk, C, Dinsmore, J & Conway., J 2021, 'Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group', Journal of Hospital Infection, vol. 110, pp. 194-200. https://doi.org/10.1016/j.jhin.2021.01.026

APA

Newsom, R., Amara, A., Hicks, A., Quint, M., Pattison, C., Bzdek, B. R., Burridge, J., Krawczyk, C., Dinsmore, J., & Conway., J. (2021). Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group. Journal of Hospital Infection, 110, 194-200. https://doi.org/10.1016/j.jhin.2021.01.026

Vancouver

Newsom R, Amara A, Hicks A, Quint M, Pattison C, Bzdek BR et al. Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group. Journal of Hospital Infection. 2021 Apr 1;110:194-200. https://doi.org/10.1016/j.jhin.2021.01.026

Author

Newsom, Richard ; Amara, Adam ; Hicks, Alexander ; Quint, Matthew ; Pattison, Chris ; Bzdek, Bryan R. ; Burridge, James ; Krawczyk, Coleman ; Dinsmore, James ; Conway., Joy. / Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group. In: Journal of Hospital Infection. 2021 ; Vol. 110. pp. 194-200.

Bibtex

@article{e7a8f80f724b4e39b845a554181ebc71,
title = "Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group",
abstract = "Background: Reducing of COVID-19 transmission relies on controlling droplet and aerosol spread. Fluorescein staining reveals microscopic droplets. We used this technique to compare the droplet spread in a standard theatre (ST) and a laminar air flow theatre (LAF).Methods: We used a {\textquoteleft}cough-generator{\textquoteright} fixed to a theatre trolley at 45-degrees. Fluorescein stained {\textquoteleft}secretions{\textquoteright} were projected onto a series of calibrated targets. These were photographed under UV light and a {\textquoteleft}source detection{\textquoteright} software measured droplet splatter size and distance.Results: The smallest droplet detected was ≅ 120 μm and the largest ≅ 24,000 μm. We detected an average of 25,862 spots in the ST, compared with 11,430 in the LAF (56% reduction). The LAF mainly affected the smaller droplets (<1000 microns). The surface area covered with droplets was: 6% at 50 cm, 1% at 2 m and 0.5% at 3 m in the ST; and 3%, 0.5% and 0.2% in the LAF respectively.Conclusion: Accurate mapping droplet spread in clinical environments is possible using fluorescein staining and image analysis. The laminar flow affected the smaller droplets but had limited effect on larger droplets in our AGP cough model. Our results indicate that LAF require similar post-surgery cleaning to those of ST and staff should consider full PPE for medium and high-risk patients.",
keywords = "Fluorescein, COVID-19, Aerosol-generating procedure (AGP), Operating theatre, Droplets, Image analysis, RCUK, NERC, NE/P018459/1",
author = "Richard Newsom and Adam Amara and Alexander Hicks and Matthew Quint and Chris Pattison and Bzdek, {Bryan R.} and James Burridge and Coleman Krawczyk and James Dinsmore and Joy Conway.",
year = "2021",
month = apr,
day = "1",
doi = "10.1016/j.jhin.2021.01.026",
language = "English",
volume = "110",
pages = "194--200",
journal = "Journal of Hospital Infection",
issn = "0195-6701",
publisher = "W. B. Saunders Ltd",

}

RIS

TY - JOUR

T1 - Comparison of droplet spread in standard and laminar flow operating theatres: SPRAY study group

AU - Newsom, Richard

AU - Amara, Adam

AU - Hicks, Alexander

AU - Quint, Matthew

AU - Pattison, Chris

AU - Bzdek, Bryan R.

AU - Burridge, James

AU - Krawczyk, Coleman

AU - Dinsmore, James

AU - Conway., Joy

PY - 2021/4/1

Y1 - 2021/4/1

N2 - Background: Reducing of COVID-19 transmission relies on controlling droplet and aerosol spread. Fluorescein staining reveals microscopic droplets. We used this technique to compare the droplet spread in a standard theatre (ST) and a laminar air flow theatre (LAF).Methods: We used a ‘cough-generator’ fixed to a theatre trolley at 45-degrees. Fluorescein stained ‘secretions’ were projected onto a series of calibrated targets. These were photographed under UV light and a ‘source detection’ software measured droplet splatter size and distance.Results: The smallest droplet detected was ≅ 120 μm and the largest ≅ 24,000 μm. We detected an average of 25,862 spots in the ST, compared with 11,430 in the LAF (56% reduction). The LAF mainly affected the smaller droplets (<1000 microns). The surface area covered with droplets was: 6% at 50 cm, 1% at 2 m and 0.5% at 3 m in the ST; and 3%, 0.5% and 0.2% in the LAF respectively.Conclusion: Accurate mapping droplet spread in clinical environments is possible using fluorescein staining and image analysis. The laminar flow affected the smaller droplets but had limited effect on larger droplets in our AGP cough model. Our results indicate that LAF require similar post-surgery cleaning to those of ST and staff should consider full PPE for medium and high-risk patients.

AB - Background: Reducing of COVID-19 transmission relies on controlling droplet and aerosol spread. Fluorescein staining reveals microscopic droplets. We used this technique to compare the droplet spread in a standard theatre (ST) and a laminar air flow theatre (LAF).Methods: We used a ‘cough-generator’ fixed to a theatre trolley at 45-degrees. Fluorescein stained ‘secretions’ were projected onto a series of calibrated targets. These were photographed under UV light and a ‘source detection’ software measured droplet splatter size and distance.Results: The smallest droplet detected was ≅ 120 μm and the largest ≅ 24,000 μm. We detected an average of 25,862 spots in the ST, compared with 11,430 in the LAF (56% reduction). The LAF mainly affected the smaller droplets (<1000 microns). The surface area covered with droplets was: 6% at 50 cm, 1% at 2 m and 0.5% at 3 m in the ST; and 3%, 0.5% and 0.2% in the LAF respectively.Conclusion: Accurate mapping droplet spread in clinical environments is possible using fluorescein staining and image analysis. The laminar flow affected the smaller droplets but had limited effect on larger droplets in our AGP cough model. Our results indicate that LAF require similar post-surgery cleaning to those of ST and staff should consider full PPE for medium and high-risk patients.

KW - Fluorescein

KW - COVID-19

KW - Aerosol-generating procedure (AGP)

KW - Operating theatre

KW - Droplets

KW - Image analysis

KW - RCUK

KW - NERC

KW - NE/P018459/1

UR - https://linkinghub.elsevier.com/retrieve/pii/S019567012100044X

U2 - 10.1016/j.jhin.2021.01.026

DO - 10.1016/j.jhin.2021.01.026

M3 - Article

VL - 110

SP - 194

EP - 200

JO - Journal of Hospital Infection

JF - Journal of Hospital Infection

SN - 0195-6701

ER -

ID: 26154071