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COVID-19: a promising cure for the global panic

Research output: Contribution to journalArticlepeer-review

  • Balachandar Vellingiri
  • Kaavya Jayaramayya
  • Mahalaxmi Iyer
  • Arul Narayanasamy
  • Vivekanandan Govindasamy
  • Bupesh Giridharan
  • Singaravelu Ganesan
  • Anila Venugopal
  • Dhivya Venkatesan
  • Harsha Ganesan
  • Kamarajan Rajagopalan
  • Ssang-Goo Cho
  • Nachimuthu Senthil Kumar
  • Mohana Devi Subramaniam
  • Pattanathu Rahman
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of the new COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and the common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.
Original languageEnglish
Article number138277
JournalScience of the Total Environment
Early online date4 Apr 2020
DOIs
Publication statusEarly online - 4 Apr 2020

Documents

  • STOTEN_D_20_04893R2_COVID_19_accepted_article

    Accepted author manuscript (Post-print), 1.98 MB, PDF document

    Due to publisher’s copyright restrictions, this document is not freely available to download from this website until: 4/04/21

    Licence: CC BY-NC-ND

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