Oxidative damage in chronic heart failure: Prevention by captoril through free radical scavenging?
Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)
The pathogenesis of heart failure is not yet fully understood. In animal models there is some evidence to suggest a role for free radicals (FRs). We have investigated malondialdehyde - LM in the plasma of patients with heart failure and found it to be raised when compared to controls. We present data to show that Captopril, a drug with an ACE inhibitory effect is a FR scavenger both in vitro and ex-vivo in patients with heart failure.
| Original language | English |
|---|---|
| Title of host publication | Antioxidants in Therapy and Preventive Medicine |
| Editors | Ingrid Emerit, Lester Packer, Christian Auclair |
| Publisher | Springer |
| Pages | 251-255 |
| Volume | 264 |
| ISBN (Electronic) | 978-1-4684-5730-8 |
| ISBN (Print) | 978-1-4684-5732-2 |
| DOIs | |
| Publication status | Published - 1990 |
Publication series
| Name | Advances in Experimental Medicine and Biology |
|---|---|
| Volume | 264 |
| ISSN (Print) | 0065-2598 |
Related information
ID: 11874069
