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Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds

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Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds. / Breese, Brynmor C.; Saynor, Zoe L.; Barker, Alan R.; Armstrong, Neil; Williams, Craig A.

In: Experimental Physiology, Vol. 104, No. 12, 01.12.2019, p. 1929-1941.

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Breese, BC, Saynor, ZL, Barker, AR, Armstrong, N & Williams, CA 2019, 'Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds', Experimental Physiology, vol. 104, no. 12, pp. 1929-1941. https://doi.org/10.1113/EP087979

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Breese, Brynmor C. ; Saynor, Zoe L. ; Barker, Alan R. ; Armstrong, Neil ; Williams, Craig A. / Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds. In: Experimental Physiology. 2019 ; Vol. 104, No. 12. pp. 1929-1941.

Bibtex

@article{08bdb86ad4e040d994748be874d514ab,
title = "Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds",
abstract = "This study investigated in nineteen male youth (mean age: 13.6 ± 1.1 y, range: 11.7–15.7 y) the relationship between pulmonary oxygen uptake ({\.V}o2) and muscle deoxygenation kinetics during moderate‐ and very heavy‐intensity {\textquoteleft}step{\textquoteright} cycling initiated from unloaded pedaling (i.e. U → M and U → VH) and moderate‐to‐very heavy‐intensity step cycling (i.e. M → VH). Pulmonary {\.V}o2 was measured breath‐by‐breath and tissue oxygenation index (TOI) of the vastus lateralis using near‐infrared spectroscopy. There were no significant differences in the phase II time constant (τ{\.V}o2p) between U → M and U → VH (23 ± 6 s vs. 25 ± 7 s; P = 0.36); however, the τ{\.V}o2p was slower during M → VH (42 ± 16 s) compared to other conditions (P < 0.001). Quadriceps TOI decreased with a faster (P < 0.01) mean response time (MRT; i.e. time delay + τ) during U → VH (14 ± 2 s) compared to U → M (22 ± 4 s) and M → VH (20 ± 6 s). The difference (Δ) between the τ{\.V}o2p and MRT‐TOI was greater during U → VH compared to U → M (12 ± 7 vs. 2 ± 7 s, P < 0.001) and during M → VH (23 ± 15 s) compared to other conditions (P < 0.02), suggesting an increased proportional speeding of fractional O2 extraction. The slowing of the τ{\.V}o2 p during M → VH relative to U → M and U → VH correlated positively with chronological age (r = 0.68 and 0.57, respectively, P < 0.01). In youth, “work‐to‐work” transitions slowed microvascular O2 delivery‐to‐O2 utilization with alterations in phase II {\.V}o2 dynamics accentuated between the ages of 11 to 15 y.",
keywords = "microvascular blood flood, muscle fibre recruitment, near-infrared spectroscopy, oxygen uptake time constant, oxygen utilization, youths",
author = "Breese, {Brynmor C.} and Saynor, {Zoe L.} and Barker, {Alan R.} and Neil Armstrong and Williams, {Craig A.}",
year = "2019",
month = dec,
day = "1",
doi = "10.1113/EP087979",
language = "English",
volume = "104",
pages = "1929--1941",
journal = "Experimental Physiology",
issn = "0958-0670",
publisher = "Wiley-Blackwell",
number = "12",

}

RIS

TY - JOUR

T1 - Relationship between (non)linear phase II pulmonary oxygen uptake kinetics with skeletal muscle oxygenation and age in 11-15 year olds

AU - Breese, Brynmor C.

AU - Saynor, Zoe L.

AU - Barker, Alan R.

AU - Armstrong, Neil

AU - Williams, Craig A.

PY - 2019/12/1

Y1 - 2019/12/1

N2 - This study investigated in nineteen male youth (mean age: 13.6 ± 1.1 y, range: 11.7–15.7 y) the relationship between pulmonary oxygen uptake (V̇o2) and muscle deoxygenation kinetics during moderate‐ and very heavy‐intensity ‘step’ cycling initiated from unloaded pedaling (i.e. U → M and U → VH) and moderate‐to‐very heavy‐intensity step cycling (i.e. M → VH). Pulmonary V̇o2 was measured breath‐by‐breath and tissue oxygenation index (TOI) of the vastus lateralis using near‐infrared spectroscopy. There were no significant differences in the phase II time constant (τV̇o2p) between U → M and U → VH (23 ± 6 s vs. 25 ± 7 s; P = 0.36); however, the τV̇o2p was slower during M → VH (42 ± 16 s) compared to other conditions (P < 0.001). Quadriceps TOI decreased with a faster (P < 0.01) mean response time (MRT; i.e. time delay + τ) during U → VH (14 ± 2 s) compared to U → M (22 ± 4 s) and M → VH (20 ± 6 s). The difference (Δ) between the τV̇o2p and MRT‐TOI was greater during U → VH compared to U → M (12 ± 7 vs. 2 ± 7 s, P < 0.001) and during M → VH (23 ± 15 s) compared to other conditions (P < 0.02), suggesting an increased proportional speeding of fractional O2 extraction. The slowing of the τV̇o2 p during M → VH relative to U → M and U → VH correlated positively with chronological age (r = 0.68 and 0.57, respectively, P < 0.01). In youth, “work‐to‐work” transitions slowed microvascular O2 delivery‐to‐O2 utilization with alterations in phase II V̇o2 dynamics accentuated between the ages of 11 to 15 y.

AB - This study investigated in nineteen male youth (mean age: 13.6 ± 1.1 y, range: 11.7–15.7 y) the relationship between pulmonary oxygen uptake (V̇o2) and muscle deoxygenation kinetics during moderate‐ and very heavy‐intensity ‘step’ cycling initiated from unloaded pedaling (i.e. U → M and U → VH) and moderate‐to‐very heavy‐intensity step cycling (i.e. M → VH). Pulmonary V̇o2 was measured breath‐by‐breath and tissue oxygenation index (TOI) of the vastus lateralis using near‐infrared spectroscopy. There were no significant differences in the phase II time constant (τV̇o2p) between U → M and U → VH (23 ± 6 s vs. 25 ± 7 s; P = 0.36); however, the τV̇o2p was slower during M → VH (42 ± 16 s) compared to other conditions (P < 0.001). Quadriceps TOI decreased with a faster (P < 0.01) mean response time (MRT; i.e. time delay + τ) during U → VH (14 ± 2 s) compared to U → M (22 ± 4 s) and M → VH (20 ± 6 s). The difference (Δ) between the τV̇o2p and MRT‐TOI was greater during U → VH compared to U → M (12 ± 7 vs. 2 ± 7 s, P < 0.001) and during M → VH (23 ± 15 s) compared to other conditions (P < 0.02), suggesting an increased proportional speeding of fractional O2 extraction. The slowing of the τV̇o2 p during M → VH relative to U → M and U → VH correlated positively with chronological age (r = 0.68 and 0.57, respectively, P < 0.01). In youth, “work‐to‐work” transitions slowed microvascular O2 delivery‐to‐O2 utilization with alterations in phase II V̇o2 dynamics accentuated between the ages of 11 to 15 y.

KW - microvascular blood flood

KW - muscle fibre recruitment

KW - near-infrared spectroscopy

KW - oxygen uptake time constant

KW - oxygen utilization

KW - youths

U2 - 10.1113/EP087979

DO - 10.1113/EP087979

M3 - Article

VL - 104

SP - 1929

EP - 1941

JO - Experimental Physiology

JF - Experimental Physiology

SN - 0958-0670

IS - 12

ER -

ID: 15536679