Towards boron neutron capture therapy: the formulation and preliminary in vitro evaluation of liposomal vehicles for the delivery of the dequalinium salt of bis-nido-carborane
Research output: Contribution to journal › Article
Liposomes of phosphatidylcholine or of dimyristoylphosphatidylcholine that incorporate bis-nido-carborane dequalinium salt are stable in physiologically relevant media and have in vitro toxicity profiles that appear to be compatible with potential therapeutic applications. These features render the structures suitable candidate boron-delivery vehicles for evaluation in the Boron Neutron Capture Therapy of cancer.
| Original language | English |
|---|---|
| Pages (from-to) | 6161-6166 |
| Journal | Bioorganic & Medicinal Chemistry Letters |
| Volume | 23 |
| Issue number | 22 |
| Early online date | 9 Sep 2013 |
| DOIs | |
| Publication status | Published - 15 Nov 2013 |
Related information
Facilities/Equipment
Atomic Force Microscopy (AFM) NanoScope 4 MultiMode
Facility/Equipment: Equipment
ID: 239399
