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Use of cluster analysis to characterize patterns of sensitization in childhood allergy

Research output: Contribution to journalLetterpeer-review

  • Carina Venter
  • Kate Maslin
  • Hongmei Zhang
  • Akhilesh Kaushal
  • William Terry
  • Veeresh K Patil
  • Tara Dean
  • Syed Hasan Arshad
Multiple tests are available to determine food and aero‐allergen sensitization (1,2), but it is unclear if distinct sensitization patterns can be determined by using a combination of three testing modalities; skin prick test (SPT), specific IgE test and component resolved diagnostic tests to characterize or identify certain clinical phenotypes. This is a novel paper utilizing sensitization clusters (SPT, specific IgE tests and component resolved diagnostics) in an unselected cohort of 10/11 year‐old children and its association with asthma, eczema, rhinitis and IgE‐mediated food allergy. A birth cohort recruited in 2001 (Isle of Wight), was followed up prospectively to 10 years of age (3) (n = 827).
Original languageEnglish
Pages (from-to)644-648
Number of pages5
JournalPediatric Allergy and Immunology
Issue number6
Early online date26 May 2018
Publication statusPublished - 1 Sep 2018


  • Multiple tests are available

    Rights statement: This is the peer reviewed version of the following article: Venter, C. , Maslin, K. , Zhang, H. , Kaushal, A. , Terry, W. , Patil, V. K., Dean, T. and Arshad, S. H. (2018), Use of cluster analysis to characterize patterns of sensitization in childhood allergy. Pediatr Allergy Immunol. Accepted Author Manuscript. . doi:10.1111/pai.12925, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

    Accepted author manuscript (Post-print), 691 KB, PDF document

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